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MGI:Pdgfc
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Pdgfc ( synonyms: PDGF-C ) | |
| Protein Name(s) | platelet-derived growth factor, C polypeptide, | |
| External Links | ||
| MGI | MGI:1859631 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005161 |
platelet-derived growth factor receptor binding |
MGI:MGI:1858279 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005161 |
platelet-derived growth factor receptor binding |
MGI:MGI:3056973 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005161 |
platelet-derived growth factor receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1858279 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0007171 |
activation of transmembrane receptor protein tyrosine kinase activity |
MGI:MGI:1858279 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0008083 |
growth factor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0339 |
F |
From MGI |
||
| GO:0008083 |
growth factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:1858279 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:3056886 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0009887 |
organ morphogenesis |
MGI:MGI:3510303 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97527 |
P |
From MGI |
||
| GO:0009887 |
organ morphogenesis |
MGI:MGI:3510303 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3510799 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043498 |
cell surface binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045740 |
positive regulation of DNA replication |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048008 |
platelet-derived growth factor receptor signaling pathway |
MGI:MGI:3056973 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048008 |
platelet-derived growth factor receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048146 |
positive regulation of fibroblast proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050730 |
regulation of peptidyl-tyrosine phosphorylation |
MGI:MGI:2182234 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0051781 |
positive regulation of cell division |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0497 |
P |
From MGI |
||
| GO:0071230 |
cellular response to amino acid stimulus |
MGI:MGI:4833768 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Li X et al. (2000) PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor. Nat Cell Biol 2: 302-9 PubMed GONUTS page
- ↑ 2.0 2.1 Fredriksson L et al. (2004) Tissue plasminogen activator is a potent activator of PDGF-CC. EMBO J 23: 3793-802 PubMed GONUTS page
- ↑ Simpson RJ et al. (2004) A classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3. J Biol Chem 279: 39789-97 PubMed GONUTS page
- ↑ 4.0 4.1 Ding H et al. (2004) A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling. Nat Genet 36: 1111-6 PubMed GONUTS page
- ↑ Saito Y et al. (2002) Protein kinase C-alpha and protein kinase C-epsilon are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor. J Biol Chem 277: 23216-22 PubMed GONUTS page
- ↑ Pogribny IP et al. (2010) Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice. Lab Invest 90: 1437-46 PubMed GONUTS page
