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MGI:Pdcd6

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Pdcd6 ( synonyms: alg-2, Alg2, MA-3, PS2 )
Protein Name(s) programmed cell death 6,
External Links
MGI MGI:109283

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005509

calcium ion binding

MGI:MGI:3763292
PMID:17214967[1]

IMP: Inferred from Mutant Phenotype

F

From MGI

GO:0005515

protein binding

MGI:MGI:2684521
PMID:14561754[2]

IPI: Inferred from Physical Interaction

UniProtKB:O08736
UniProtKB:Q8C3Q9

F

From MGI

GO:0005515

protein binding

MGI:MGI:3609918
PMID:11591653[3]

IPI: Inferred from Physical Interaction

UniProtKB:P70389
UniProtKB:Q9DC67
UniProtKB:Q9CQ85
UniProtKB:Q9D0C1

F

From MGI

GO:0005515

protein binding

MGI:MGI:4456958
PMID:11606059[4]

IPI: Inferred from Physical Interaction

UniProtKB:P25445

F

From MGI

GO:0005625

soluble fraction

MGI:MGI:2684521
PMID:14561754[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75340

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3763292
PMID:17214967[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75340

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75340

C

From MGI

GO:0005792

microsome

MGI:MGI:2684521
PMID:14561754[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006886

intracellular protein transport

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75340

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:81240
PMID:8560270[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006919

activation of cysteine-type endopeptidase activity involved in apoptotic process

MGI:MGI:2684521
PMID:14561754[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0031410

cytoplasmic vesicle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75340

C

From MGI

GO:0033554

cellular response to stress

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75340

P

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:1333264
PMID:10200558[6]

IPI: Inferred from Physical Interaction

UniProtKB:P12815

F

From MGI

GO:0046983

protein dimerization activity

MGI:MGI:1333264
PMID:10200558[6]

IPI: Inferred from Physical Interaction

UniProtKB:Q9WU78

F

From MGI

GO:0046983

protein dimerization activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75340

F

From MGI

GO:0048306

calcium-dependent protein binding

MGI:MGI:3763292
PMID:17214967[1]

IPI: Inferred from Physical Interaction

UniProtKB:O94979

F

From MGI

GO:0048306

calcium-dependent protein binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75340

F

From MGI

GO:0051592

response to calcium ion

MGI:MGI:3763292
PMID:17214967[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060090

binding, bridging

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75340

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 la Cour JM et al. (2007) ALG-2 oscillates in subcellular localization, unitemporally with calcium oscillations. Biochem Biophys Res Commun 353: 1063-7 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Rao RV et al. (2004) Molecular components of a cell death pathway activated by endoplasmic reticulum stress. J Biol Chem 279: 177-87 PubMed GONUTS page
  3. Suzuki H et al. (2001) Protein-protein interaction panel using mouse full-length cDNAs. Genome Res 11: 1758-65 PubMed GONUTS page
  4. Jung YS et al. (2001) Apoptosis-linked gene 2 binds to the death domain of Fas and dissociates from Fas during Fas-mediated apoptosis in Jurkat cells. Biochem Biophys Res Commun 288: 420-6 PubMed GONUTS page
  5. Vito P et al. (1996) Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science 271: 521-5 PubMed GONUTS page
  6. 6.0 6.1 Missotten M et al. (1999) Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptosis-linked-gene 2 (ALG-2) protein. Cell Death Differ 6: 124-9 PubMed GONUTS page
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