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MGI:Pcsk1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Pcsk1 ( synonyms: Nec-1, Nec1, PC1, PC3, Phpp-1, prohormone convertase 1/3, SPC3 ) | |
| Protein Name(s) | proprotein convertase subtilisin/kexin type 1, | |
| External Links | ||
| MGI | MGI:97511 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004175 |
endopeptidase activity |
MGI:MGI:3807770 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004175 |
endopeptidase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004252 |
serine-type endopeptidase activity |
MGI:MGI:3773775 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:3793923 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005791 |
rough endoplasmic reticulum |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005794 |
Golgi apparatus |
MGI:MGI:4459044 |
PANTHER:PTHR10795 |
C |
From MGI |
|||
| GO:0005802 |
trans-Golgi network |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006508 |
proteolysis |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008233 |
peptidase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0645 |
F |
From MGI |
||
| GO:0008236 |
serine-type peptidase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0720 |
F |
From MGI |
||
| GO:0016485 |
protein processing |
MGI:MGI:3807770 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016486 |
peptide hormone processing |
MGI:MGI:3773775 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016486 |
peptide hormone processing |
MGI:MGI:3807770 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016486 |
peptide hormone processing |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016540 |
protein autoprocessing |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0030141 |
secretory granule |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030425 |
dendrite |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031410 |
cytoplasmic vesicle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0968 |
C |
From MGI |
||
| GO:0032403 |
protein complex binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043005 |
neuron projection |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043025 |
neuronal cell body |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043043 |
peptide biosynthetic process |
MGI:MGI:3773775 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043559 |
insulin binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043679 |
axon terminus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0048471 |
perinuclear region of cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0050714 |
positive regulation of protein secretion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051087 |
chaperone binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
|
colocalizes_with |
GO:0030141 |
secretory granule |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Schaner P et al. (1997) Processing of prothyrotropin-releasing hormone by the family of prohormone convertases. J Biol Chem 272: 19958-68 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Breslin MB et al. (1993) Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin. J Biol Chem 268: 27084-93 PubMed GONUTS page
- ↑ Benjannet S et al. (1993) Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1 and PC2. Biochem J 294 ( Pt 3): 735-43 PubMed GONUTS page
acdeghi |
np |
p cont.rs
t |
