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MGI:Pcnt
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Pcnt ( synonyms: m239Asp, m275Asp, Pcnt2 ) | |
| Protein Name(s) | pericentrin (kendrin), | |
| External Links | ||
| MGI | MGI:102722 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000226 |
microtubule cytoskeleton organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001701 |
in utero embryonic development |
MGI:MGI:4438783 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3799303 |
P |
From MGI |
||
| GO:0001764 |
neuron migration |
MGI:MGI:4438783 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3799303 |
P |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:4454949 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5142395 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005516 |
calmodulin binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0112 |
F |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:2150845 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:3057091 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:3762422 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:3773587 |
ISO: Inferred from Sequence Orthology |
RefSeq:NM_006031 |
C |
From MGI |
||
| GO:0005813 |
centrosome |
MGI:MGI:4438783 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:4457834 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005814 |
centriole |
MGI:MGI:3037622 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005814 |
centriole |
MGI:MGI:3053250 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005815 |
microtubule organizing center |
MGI:MGI:65190 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0005874 |
microtubule |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0493 |
C |
From MGI |
||
| GO:0006915 |
apoptotic process |
MGI:MGI:4438783 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3799303 |
P |
From MGI |
||
| GO:0007051 |
spindle organization |
MGI:MGI:65190 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0021696 |
cerebellar cortex morphogenesis |
MGI:MGI:4438783 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3799303 |
P |
From MGI |
||
| GO:0021772 |
olfactory bulb development |
MGI:MGI:4438783 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3799303 |
P |
From MGI |
||
| GO:0035108 |
limb morphogenesis |
MGI:MGI:4438783 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3799303 |
P |
From MGI |
||
| GO:0035264 |
multicellular organism growth |
MGI:MGI:4438783 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3799303 |
P |
From MGI |
||
| GO:0042384 |
cilium assembly |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045171 |
intercellular bridge |
MGI:MGI:4457834 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0048854 |
brain morphogenesis |
MGI:MGI:4438783 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3799303 |
P |
From MGI |
||
| GO:0061351 |
neural precursor cell proliferation |
MGI:MGI:4438783 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3799303 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Endoh-Yamagami S et al. (2010) A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice. Dev Biol 340: 41-53 PubMed GONUTS page
- ↑ Buchman JJ et al. (2010) Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex. Neuron 66: 386-402 PubMed GONUTS page
- ↑ Tong JK et al. (1998) Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex. Nature 395: 917-21 PubMed GONUTS page
- ↑ Sutherland HG et al. (2001) Large-scale identification of mammalian proteins localized to nuclear sub-compartments. Hum Mol Genet 10: 1995-2011 PubMed GONUTS page
- ↑ Goto M & Eddy EM (2004) Speriolin is a novel spermatogenic cell-specific centrosomal protein associated with the seventh WD motif of Cdc20. J Biol Chem 279: 42128-38 PubMed GONUTS page
- ↑ Xie Z et al. (2007) Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool. Neuron 56: 79-93 PubMed GONUTS page
- ↑ Zhu F et al. (2008) The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis. Curr Biol 18: 136-41 PubMed GONUTS page
- ↑ 8.0 8.1 Chang YC et al. (2010) Characterization of centrosomal proteins Cep55 and pericentrin in intercellular bridges of mouse testes. J Cell Biochem 109: 1274-85 PubMed GONUTS page
- ↑ Klezovitch O et al. (2004) Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice. Genes Dev 18: 559-71 PubMed GONUTS page
- ↑ Jurczyk A et al. (2004) Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly. J Cell Biol 166: 637-43 PubMed GONUTS page
- ↑ 11.0 11.1 Doxsey SJ et al. (1994) Pericentrin, a highly conserved centrosome protein involved in microtubule organization. Cell 76: 639-50 PubMed GONUTS page
