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MGI:Paxip1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Paxip1 ( synonyms: D5Ertd149e, PTIP ) | |
| Protein Name(s) | PAX interacting (with transcription-activation domain) protein 1, | |
| External Links | ||
| MGI | MGI:1890430 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000416 |
positive regulation of histone H3-K36 methylation |
MGI:MGI:4821506 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0001570 |
vasculogenesis |
MGI:MGI:3814106 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:1934164 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3844416 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1934164 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3718866 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4821506 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006281 |
DNA repair |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From MGI |
||
| GO:0006310 |
DNA recombination |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0233 |
P |
From MGI |
||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006974 |
response to DNA damage stimulus |
MGI:MGI:3718866 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0010212 |
response to ionizing radiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030330 |
DNA damage response, signal transduction by p53 class mediator |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031398 |
positive regulation of protein ubiquitination |
MGI:MGI:4887323 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0035066 |
positive regulation of histone acetylation |
MGI:MGI:4821506 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0035097 |
histone methyltransferase complex |
MGI:MGI:3718866 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0035097 |
histone methyltransferase complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043542 |
endothelial cell migration |
MGI:MGI:3814106 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0045830 |
positive regulation of isotype switching |
MGI:MGI:4821506 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0051568 |
histone H3-K4 methylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051571 |
positive regulation of histone H3-K4 methylation |
MGI:MGI:4354659 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0051571 |
positive regulation of histone H3-K4 methylation |
MGI:MGI:4821506 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0060261 |
positive regulation of transcription initiation from RNA polymerase II promoter |
MGI:MGI:4354659 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0060261 |
positive regulation of transcription initiation from RNA polymerase II promoter |
MGI:MGI:4821506 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0060261 |
positive regulation of transcription initiation from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060612 |
adipose tissue development |
MGI:MGI:4354659 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0060717 |
chorion development |
MGI:MGI:3814106 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Daniel JA et al. (2010) PTIP promotes chromatin changes critical for immunoglobulin class switch recombination. Science 329: 917-23 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Mu W et al. (2008) An allelic series uncovers novel roles of the BRCT domain-containing protein PTIP in mouse embryonic vascular development. Mol Cell Biol 28: 6439-51 PubMed GONUTS page
- ↑ 3.0 3.1 Lechner MS et al. (2000) PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin. Nucleic Acids Res 28: 2741-51 PubMed GONUTS page
- ↑ Gong Z et al. (2009) Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage. J Biol Chem 284: 7284-93 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Cho YW et al. (2007) PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex. J Biol Chem 282: 20395-406 PubMed GONUTS page
- ↑ Göhler T et al. (2008) PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage. DNA Repair (Amst) 7: 775-87 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Cho YW et al. (2009) Histone methylation regulator PTIP is required for PPARgamma and C/EBPalpha expression and adipogenesis. Cell Metab 10: 27-39 PubMed GONUTS page
