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MGI:Patz1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Patz1 ( synonyms: MAZR, POZ-AT hook-zinc finger protein, Zfp278 )
Protein Name(s) POZ (BTB) and AT hook containing zinc finger 1,
External Links
MGI MGI:1891832

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

MGI:MGI:3662835
PMID:16491076[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003682

chromatin binding

MGI:MGI:3662835
PMID:16491076[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:3662835
PMID:16491076[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q60974

F

From MGI

GO:0005515

protein binding

MGI:MGI:3688344
PMID:15102471[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q6PDN3

F

From MGI

GO:0005634

nucleus

MGI:MGI:1934388
PMID:10713105[3]

ISS: Inferred from Sequence or Structural Similarity

C

From MGI

GO:0005634

nucleus

MGI:MGI:3662835
PMID:16491076[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:3778730
PMID:18241078[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:3662835
PMID:16491076[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q60974

P

From MGI

GO:0007283

spermatogenesis

MGI:MGI:3778730
PMID:18241078[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795851

P

From MGI

GO:0008584

male gonad development

MGI:MGI:3778730
PMID:18241078[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795851

P

From MGI

GO:0010468

regulation of gene expression

MGI:MGI:3662835
PMID:16491076[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030217

T cell differentiation

MGI:MGI:3662835
PMID:16491076[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:1934388
PMID:10713105[3]

ISS: Inferred from Sequence or Structural Similarity

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:1889875
PMID:10669750[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Bilic I et al. (2006) Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR. Nat Immunol 7: 392-400 PubMed GONUTS page
  2. Papin J & Subramaniam S (2004) Bioinformatics and cellular signaling. Curr Opin Biotechnol 15: 78-81 PubMed GONUTS page
  3. 3.0 3.1 Fedele M et al. (2000) A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor. J Biol Chem 275: 7894-901 PubMed GONUTS page
  4. 4.0 4.1 4.2 Fedele M et al. (2008) PATZ1 gene has a critical role in the spermatogenesis and testicular tumours. J Pathol 215: 39-47 PubMed GONUTS page
  5. Kobayashi A et al. (2000) A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domain. Mol Cell Biol 20: 1733-46 PubMed GONUTS page
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