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MGI:Pak3

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Pak3 ( synonyms: PAK-3 )
Protein Name(s) p21 protein (Cdc42/Rac)-activated kinase 3,
External Links
MGI MGI:1339656

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000165

MAPK cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75914

P

From MGI

GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000187

activation of MAPK activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75914

P

From MGI

GO:0003824

catalytic activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0021

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62829

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

From MGI

GO:0004708

MAP kinase kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75914

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441
InterPro:IPR002290

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62829

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007409

axonogenesis

MGI:MGI:4940954
PMID:21115725[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0008152

metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0021

P

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016358

dendrite development

MGI:MGI:4940954
PMID:21115725[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0017048

Rho GTPase binding

MGI:MGI:3843447
PMID:10445846[2]

IPI: Inferred from Physical Interaction

UniProtKB:P17081

F

From MGI

GO:0017124

SH3 domain binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0729

F

From MGI

GO:0030833

regulation of actin filament polymerization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O75914

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0051020

GTPase binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62829

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Huang W et al. (2011) p21-Activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic properties. Mol Cell Biol 31: 388-403 PubMed GONUTS page
  2. Murphy GA et al. (1999) Cellular functions of TC10, a Rho family GTPase: regulation of morphology, signal transduction and cell growth. Oncogene 18: 3831-45 PubMed GONUTS page
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