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MGI:P4hb

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) P4hb ( synonyms: ERp59, Pdia1, protein disulfide isomerase, Thbp )
Protein Name(s) prolyl 4-hydroxylase, beta polypeptide,
External Links
MGI MGI:97464

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003756

protein disulfide isomerase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04785

F

From MGI

GO:0004656

procollagen-proline 4-dioxygenase activity

MGI:MGI:72931
PMID:7753822[1]

ISO: Inferred from Sequence Orthology

UniProtKB:P07237

F

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:1197543
PMID:9493907[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:1314509
PMID:9806833[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:3575843
PMID:15767678[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:3626170
PMID:15767459[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:3793881
PMID:18094359[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:E7EPA8

C

From MGI

GO:0005792

microsome

MGI:MGI:2684521
PMID:14561754[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005793

endoplasmic reticulum-Golgi intermediate compartment

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P07237

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0006662

glycerol ether metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005746

P

From MGI

GO:0009055

electron carrier activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005746

F

From MGI

GO:0009986

cell surface

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P07237

C

From MGI

GO:0015035

protein disulfide oxidoreductase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005746

F

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016853

isomerase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0413

F

From MGI

GO:0016853

isomerase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005788
InterPro:IPR005792

F

From MGI

GO:0018401

peptidyl-proline hydroxylation to 4-hydroxy-L-proline

MGI:MGI:72931
PMID:7753822[1]

ISO: Inferred from Sequence Orthology

UniProtKB:P07237

P

From MGI

GO:0045454

cell redox homeostasis

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005746
InterPro:IPR017937
InterPro:IPR013766

P

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04785

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Helaakoski T et al. (1995) Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit. Proc Natl Acad Sci U S A 92: 4427-31 PubMed GONUTS page
  2. Miyaishi O et al. (1998) Elevated expression of PDI family proteins during differentiation of mouse F9 teratocarcinoma cells. J Cell Biochem 68: 436-45 PubMed GONUTS page
  3. Nakamura T et al. (1998) Molecular cloning, characterization, and chromosomal localization of FKBP23, a novel FK506-binding protein with Ca2+-binding ability. Genomics 54: 89-98 PubMed GONUTS page
  4. Kelkar N et al. (2005) Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways. Mol Cell Biol 25: 2733-43 PubMed GONUTS page
  5. Goodchild RE & Dauer WT (2005) The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein. J Cell Biol 168: 855-62 PubMed GONUTS page
  6. De La Chesnaye E et al. (2008) Fbxw15/Fbxo12J is an F-box protein-encoding gene selectively expressed in oocytes of the mouse ovary. Biol Reprod 78: 714-25 PubMed GONUTS page
  7. Rao RV et al. (2004) Molecular components of a cell death pathway activated by endoplasmic reticulum stress. J Biol Chem 279: 177-87 PubMed GONUTS page
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