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MGI:P2ry12
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | P2ry12 ( synonyms: P2Y12 ) | |
| Protein Name(s) | purinergic receptor P2Y, G-protein coupled 12, | |
| External Links | ||
| MGI | MGI:1918089 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001609 |
G-protein coupled adenosine receptor activity |
MGI:MGI:2136079 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2445936 |
F |
From MGI |
||
| GO:0001621 |
ADP receptor activity |
MGI:MGI:2136079 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2445936 |
F |
From MGI |
||
| GO:0001621 |
ADP receptor activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
F |
From MGI |
||
| GO:0001973 |
adenosine receptor signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
P |
From MGI |
||
| GO:0004871 |
signal transducer activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
F |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0004930 |
G-protein coupled receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
F |
From MGI |
||
| GO:0005622 |
intracellular |
MGI:MGI:2136079 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2445936 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0005887 |
integral to plasma membrane |
MGI:MGI:2136079 |
IC: Inferred by Curator |
GO:0001609 |
C |
From MGI |
||
| GO:0005901 |
caveola |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
C |
From MGI |
||
| GO:0007165 |
signal transduction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
P |
From MGI |
||
| GO:0007188 |
G-protein signaling, coupled to cAMP nucleotide second messenger |
MGI:MGI:2136079 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2445936 |
P |
From MGI |
||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
C |
From MGI |
||
| GO:0009925 |
basal plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
C |
From MGI |
||
| GO:0010700 |
negative regulation of norepinephrine secretion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0030030 |
cell projection organization |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
P |
From MGI |
||
| GO:0030168 |
platelet activation |
MGI:MGI:2136079 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2445936 |
P |
From MGI |
||
| GO:0043270 |
positive regulation of ion transport |
MGI:MGI:3699674 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:105049 |
P |
From MGI |
||
| GO:0043491 |
protein kinase B signaling cascade |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
P |
From MGI |
||
| GO:0045028 |
G-protein coupled purinergic nucleotide receptor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0045596 |
negative regulation of cell differentiation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
P |
From MGI |
||
| GO:0051927 |
negative regulation of calcium ion transport via voltage-gated calcium channel activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
P |
From MGI |
||
| GO:0070527 |
platelet aggregation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
P |
From MGI |
||
| GO:0070588 |
calcium ion transmembrane transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
P |
From MGI |
||
| GO:0071805 |
potassium ion transmembrane transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
P |
From MGI |
||
|
colocalizes_with |
GO:0005739 |
mitochondrion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_073637 |
C |
From MGI |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Foster CJ et al. (2001) Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs. J Clin Invest 107: 1591-8 PubMed GONUTS page
- ↑ Tolhurst G et al. (2005) Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling. Blood 106: 1644-51 PubMed GONUTS page
