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MGI:P2ry1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) P2ry1 ( synonyms: P2Y1, P2Y1 receptor )
Protein Name(s) purinergic receptor P2Y, G-protein coupled 1,
External Links
MGI MGI:105049

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004871

signal transducer activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0004930

G-protein coupled receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0297

F

From MGI

GO:0005524

ATP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

F

From MGI

GO:0005886

plasma membrane

MGI:MGI:3577111
PMID:15670583[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0007165

signal transduction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

P

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0007193

inhibition of adenylate cyclase activity by G-protein signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0007204

elevation of cytosolic calcium ion concentration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0009612

response to mechanical stimulus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0010469

regulation of receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0010700

negative regulation of norepinephrine secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000276
InterPro:IPR002286
InterPro:IPR000142

C

From MGI

GO:0016323

basolateral plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

C

From MGI

GO:0016324

apical plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

C

From MGI

GO:0019233

sensory perception of pain

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0030425

dendrite

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

C

From MGI

GO:0031686

A1 adenosine receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

F

From MGI

GO:0032962

positive regulation of inositol trisphosphate biosynthetic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0035589

G-protein coupled purinergic nucleotide receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0042312

regulation of vasodilation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0042755

eating behavior

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0043270

positive regulation of ion transport

MGI:MGI:3699674
PMID:15914557[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:1098235
MGI:MGI:1918089

P

From MGI

GO:0043270

positive regulation of ion transport

MGI:MGI:3699674
PMID:15914557[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2181709

P

From MGI

GO:0043531

ADP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

F

From MGI

GO:0044297

cell body

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

C

From MGI

GO:0045028

G-protein coupled purinergic nucleotide receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

F

From MGI

GO:0046887

positive regulation of hormone secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

F

From MGI

GO:0051100

negative regulation of binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

GO:0060406

positive regulation of penile erection

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

P

From MGI

colocalizes_with

GO:0005739

mitochondrion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49651

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Coutinho-Silva R et al. (2005) Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages. Biochem Pharmacol 69: 641-55 PubMed GONUTS page
  2. 2.0 2.1 Tolhurst G et al. (2005) Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling. Blood 106: 1644-51 PubMed GONUTS page
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