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MGI:Osm

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Osm ( synonyms: OncoM )
Protein Name(s) oncostatin M,
External Links
MGI MGI:104749

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005125

cytokine activity

MGI:MGI:3036919
PMID:15012602[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005125

cytokine activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P13725

F

From MGI

GO:0005147

oncostatin-M receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P13725

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001581
InterPro:IPR019827

C

From MGI

GO:0005615

extracellular space

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0202

C

From MGI

GO:0005900

oncostatin-M receptor complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P13725

C

From MGI

GO:0006915

apoptotic process

MGI:MGI:3036919
PMID:15012602[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006955

immune response

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001581
InterPro:IPR019827

P

From MGI

GO:0007422

peripheral nervous system development

MGI:MGI:3574134
PMID:14985435[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3574987

P

From MGI

GO:0008083

growth factor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P13725

F

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P13725

P

From MGI

GO:0009408

response to heat

MGI:MGI:3574134
PMID:14985435[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3574987

P

From MGI

GO:0033138

positive regulation of peptidyl-serine phosphorylation

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P13725

P

From MGI

GO:0040008

regulation of growth

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0341

P

From MGI

GO:0042503

tyrosine phosphorylation of Stat3 protein

MGI:MGI:3036919
PMID:15012602[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0042506

tyrosine phosphorylation of Stat5 protein

MGI:MGI:3036919
PMID:15012602[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0042508

tyrosine phosphorylation of Stat1 protein

MGI:MGI:3036919
PMID:15012602[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0043410

positive regulation of MAPK cascade

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P13725

P

From MGI

GO:0045835

negative regulation of meiosis

MGI:MGI:1929792
PMID:11203703[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P13725

P

From MGI

GO:0046888

negative regulation of hormone secretion

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P13725

P

From MGI

GO:0048266

behavioral response to pain

MGI:MGI:3574134
PMID:14985435[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3574987

P

From MGI

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P13725

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Auernhammer CJ et al. (2004) The oncostatin M receptor/gp130 ligand murine oncostatin M induces apoptosis in adrenocortical Y-1 tumor cells. J Endocrinol 180: 479-86 PubMed GONUTS page
  2. 2.0 2.1 2.2 Morikawa Y et al. (2004) Essential function of oncostatin m in nociceptive neurons of dorsal root ganglia. J Neurosci 24: 1941-7 PubMed GONUTS page
  3. Chuma S & Nakatsuji N (2001) Autonomous transition into meiosis of mouse fetal germ cells in vitro and its inhibition by gp130-mediated signaling. Dev Biol 229: 468-79 PubMed GONUTS page
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