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MGI:Ophn1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ophn1 | |
| Protein Name(s) | oligophrenin 1, | |
| External Links | ||
| MGI | MGI:2151070 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003779 |
actin binding |
MGI:MGI:2674209 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005096 |
GTPase activator activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0343 |
F |
From MGI |
||
| GO:0005100 |
Rho GTPase activator activity |
MGI:MGI:4359148 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4359148 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005543 |
phospholipid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0006897 |
endocytosis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0254 |
P |
From MGI |
||
| GO:0007165 |
signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007399 |
nervous system development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0524 |
P |
From MGI |
||
| GO:0008093 |
cytoskeletal adaptor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0015629 |
actin cytoskeleton |
MGI:MGI:2674209 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0017124 |
SH3 domain binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0030036 |
actin cytoskeleton organization |
MGI:MGI:2674209 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0030100 |
regulation of endocytosis |
MGI:MGI:4359148 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0032321 |
positive regulation of Rho GTPase activity |
MGI:MGI:4359148 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0035255 |
ionotropic glutamate receptor binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001101318 |
F |
From MGI |
||
| GO:0042995 |
cell projection |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0966 |
C |
From MGI |
||
| GO:0043195 |
terminal button |
MGI:MGI:4359148 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043547 |
positive regulation of GTPase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0343 |
P |
From MGI |
||
| GO:0045202 |
synapse |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0770 |
C |
From MGI |
||
| GO:0046847 |
filopodium assembly |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0048488 |
synaptic vesicle endocytosis |
MGI:MGI:4359148 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:700009 |
P |
From MGI |
||
| GO:0048488 |
synaptic vesicle endocytosis |
MGI:MGI:4359148 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0051966 |
regulation of synaptic transmission, glutamatergic |
MGI:MGI:4359148 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Fauchereau F et al. (2003) The RhoGAP activity of OPHN1, a new F-actin-binding protein, is negatively controlled by its amino-terminal domain. Mol Cell Neurosci 23: 574-86 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Nakano-Kobayashi A et al. (2009) The Rho-linked mental retardation protein OPHN1 controls synaptic vesicle endocytosis via endophilin A1. Curr Biol 19: 1133-9 PubMed GONUTS page
