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MGI:Onecut2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Onecut2 ( synonyms: OC-2, Oc2 )
Protein Name(s) one cut domain, family member 2,
External Links
MGI MGI:1891408

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001889

liver development

MGI:MGI:3763866
PMID:17936262[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1196423

P

From MGI

GO:0001952

regulation of cell-matrix adhesion

MGI:MGI:3763866
PMID:17936262[1]

IGI: Inferred from Genetic Interaction

P

From MGI

GO:0002064

epithelial cell development

MGI:MGI:3723392
PMID:16472605[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3588425

P

From MGI

GO:0003677

DNA binding

MGI:MGI:2178162
PMID:11944891[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:3710726
PMID:17400205[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005634

nucleus

MGI:MGI:3710726
PMID:17400205[4]

IC: Inferred by Curator

GO:0045944
GO:0003700

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

P

From MGI

GO:0009653

anatomical structure morphogenesis

MGI:MGI:3588024
PMID:16103213[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3588425

P

From MGI

GO:0030335

positive regulation of cell migration

MGI:MGI:3763866
PMID:17936262[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1196423

P

From MGI

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

MGI:MGI:3588024
PMID:16103213[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:1196423

P

From MGI

GO:0031016

pancreas development

MGI:MGI:3710726
PMID:17400205[4]

IGI: Inferred from Genetic Interaction

MGI:MGI:1196423

P

From MGI

GO:0031018

endocrine pancreas development

MGI:MGI:3710726
PMID:17400205[4]

IGI: Inferred from Genetic Interaction

MGI:MGI:1196423

P

From MGI

GO:0042384

cilium assembly

MGI:MGI:3723392
PMID:16472605[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3588425

P

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

F

From MGI

GO:0045165

cell fate commitment

MGI:MGI:3588024
PMID:16103213[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:1196423

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3710726
PMID:17400205[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0048935

peripheral nervous system neuron development

MGI:MGI:3761972
PMID:17698011[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3588425

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Margagliotti S et al. (2007) The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration. Dev Biol 311: 579-89 PubMed GONUTS page
  2. 2.0 2.1 Pierreux CE et al. (2006) The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology 130: 532-41 PubMed GONUTS page
  3. Vanhorenbeeck V et al. (2002) OC-3, a novel mammalian member of the ONECUT class of transcription factors. Biochem Biophys Res Commun 292: 848-54 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Vanhorenbeeck V et al. (2007) Role of the Onecut transcription factors in pancreas morphogenesis and in pancreatic and enteric endocrine differentiation. Dev Biol 305: 685-94 PubMed GONUTS page
  5. 5.0 5.1 5.2 Clotman F et al. (2005) Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors. Genes Dev 19: 1849-54 PubMed GONUTS page
  6. Hodge LK et al. (2007) Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps. Neuron 55: 572-86 PubMed GONUTS page
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