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MGI:Obfc1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Obfc1
Protein Name(s) oligonucleotide/oligosaccharide-binding fold containing 1,
External Links
MGI MGI:1915581

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000723

telomere maintenance

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H668

P

From MGI

GO:0000781

chromosome, telomeric region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0779

C

From MGI

GO:0000784

nuclear chromosome, telomeric region

MGI:MGI:4441108
PMID:19854130[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0000784

nuclear chromosome, telomeric region

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H668

C

From MGI

GO:0003676

nucleic acid binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004365

F

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From MGI

GO:0003697

single-stranded DNA binding

MGI:MGI:4441245
PMID:19119139[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:4441116
PMID:19648609[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q5EE38

F

From MGI

GO:0005515

protein binding

MGI:MGI:4441245
PMID:19119139[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q5SUQ9

F

From MGI

GO:0005634

nucleus

MGI:MGI:4441108
PMID:19854130[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4441245
PMID:19119139[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H668

C

From MGI

GO:0005694

chromosome

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0158

C

From MGI

GO:0010833

telomere maintenance via telomere lengthening

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H668

P

From MGI

GO:0043047

single-stranded telomeric DNA binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H668

F

From MGI

GO:0043231

intracellular membrane-bounded organelle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H668

C

From MGI

GO:0045111

intermediate filament cytoskeleton

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H668

C

From MGI

GO:0045740

positive regulation of DNA replication

MGI:MGI:4441245
PMID:19119139[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0070188

Stn1-Ten1 complex

MGI:MGI:4441108
PMID:19854130[1]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Miyake Y et al. (2009) RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway. Mol Cell 36: 193-206 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Casteel DE et al. (2009) A DNA polymerase-{alpha}{middle dot}primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells. J Biol Chem 284: 5807-18 PubMed GONUTS page
  3. Wan M et al. (2009) OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation. J Biol Chem 284: 26725-31 PubMed GONUTS page
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