![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Nupr1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Nupr1 ( synonyms: Com1, p8 ) | |
| Protein Name(s) | nuclear protein 1, | |
| External Links | ||
| MGI | MGI:1891834 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002526 |
acute inflammatory response |
MGI:MGI:3037507 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3784016 |
P |
From MGI |
||
| GO:0003682 |
chromatin binding |
MGI:MGI:4360820 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4360820 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:3784021 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3784016 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006461 |
protein complex assembly |
MGI:MGI:4360820 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0006473 |
protein acetylation |
MGI:MGI:4360820 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0008584 |
male gonad development |
MGI:MGI:3814794 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3784016 |
P |
From MGI |
||
| GO:0009636 |
response to toxin |
MGI:MGI:3037507 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3784016 |
P |
From MGI |
||
| GO:0016049 |
cell growth |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031401 |
positive regulation of protein modification process |
MGI:MGI:4365856 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0035914 |
skeletal muscle cell differentiation |
MGI:MGI:4360820 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0042771 |
DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis |
MGI:MGI:3784021 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3784016 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:3784021 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3784016 |
P |
From MGI |
||
| GO:0045786 |
negative regulation of cell cycle |
MGI:MGI:4360820 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0048147 |
negative regulation of fibroblast proliferation |
MGI:MGI:3784021 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3784016 |
P |
From MGI |
||
| GO:2000194 |
regulation of female gonad development |
MGI:MGI:3814794 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3784016 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Vasseur S et al. (2004) p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I. J Biol Chem 279: 7199-207 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Sambasivan R et al. (2009) The small chromatin-binding protein p8 coordinates the association of anti-proliferative and pro-myogenic proteins at the myogenin promoter. J Cell Sci 122: 3481-91 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Vasseur S et al. (2002) p8-deficient fibroblasts grow more rapidly and are more resistant to adriamycin-induced apoptosis. Oncogene 21: 1685-94 PubMed GONUTS page
- ↑ 4.0 4.1 Million Passe CM et al. (2008) Loss of the protein NUPR1 (p8) leads to delayed LHB expression, delayed ovarian maturation, and testicular development of a sertoli-cell-only syndrome-like phenotype in mice. Biol Reprod 79: 598-607 PubMed GONUTS page
- ↑ Alison MR (2009) Stem cells and cancer in the aerodigestive tract. Eur J Cancer 45 Suppl 1: 175-85 PubMed GONUTS page