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MGI:Nupr1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Nupr1 ( synonyms: Com1, p8 )
Protein Name(s) nuclear protein 1,
External Links
MGI MGI:1891834

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002526

acute inflammatory response

MGI:MGI:3037507
PMID:14660681[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3784016

P

From MGI

GO:0003682

chromatin binding

MGI:MGI:4360820
PMID:19723804[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:4360820
PMID:19723804[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q61656
UniProtKB:E9PYJ8
UniProtKB:P10085

F

From MGI

GO:0005622

intracellular

MGI:MGI:3784021
PMID:11896600[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3784016

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60356

C

From MGI

GO:0006461

protein complex assembly

MGI:MGI:4360820
PMID:19723804[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0006473

protein acetylation

MGI:MGI:4360820
PMID:19723804[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0008584

male gonad development

MGI:MGI:3814794
PMID:18495683[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3784016

P

From MGI

GO:0009636

response to toxin

MGI:MGI:3037507
PMID:14660681[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3784016

P

From MGI

GO:0016049

cell growth

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60356

P

From MGI

GO:0031401

positive regulation of protein modification process

MGI:MGI:4365856
PMID:19775616[5]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0035914

skeletal muscle cell differentiation

MGI:MGI:4360820
PMID:19723804[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0042771

DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis

MGI:MGI:3784021
PMID:11896600[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3784016

P

From MGI

GO:0043065

positive regulation of apoptotic process

MGI:MGI:3784021
PMID:11896600[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3784016

P

From MGI

GO:0045786

negative regulation of cell cycle

MGI:MGI:4360820
PMID:19723804[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0048147

negative regulation of fibroblast proliferation

MGI:MGI:3784021
PMID:11896600[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3784016

P

From MGI

GO:2000194

regulation of female gonad development

MGI:MGI:3814794
PMID:18495683[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3784016

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Vasseur S et al. (2004) p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I. J Biol Chem 279: 7199-207 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Sambasivan R et al. (2009) The small chromatin-binding protein p8 coordinates the association of anti-proliferative and pro-myogenic proteins at the myogenin promoter. J Cell Sci 122: 3481-91 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Vasseur S et al. (2002) p8-deficient fibroblasts grow more rapidly and are more resistant to adriamycin-induced apoptosis. Oncogene 21: 1685-94 PubMed GONUTS page
  4. 4.0 4.1 Million Passe CM et al. (2008) Loss of the protein NUPR1 (p8) leads to delayed LHB expression, delayed ovarian maturation, and testicular development of a sertoli-cell-only syndrome-like phenotype in mice. Biol Reprod 79: 598-607 PubMed GONUTS page
  5. Alison MR (2009) Stem cells and cancer in the aerodigestive tract. Eur J Cancer 45 Suppl 1: 175-85 PubMed GONUTS page
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