GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Numbl
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Numbl ( synonyms: nbl ) | |
| Protein Name(s) | numb-like, | |
| External Links | ||
| MGI | MGI:894702 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005625 |
soluble fraction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001029060 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:3526784 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:892754 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007399 |
nervous system development |
MGI:MGI:2683798 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429686 |
P |
From MGI |
||
| GO:0007405 |
neuroblast proliferation |
MGI:MGI:2389562 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:107423 |
P |
From MGI |
||
| GO:0007409 |
axonogenesis |
MGI:MGI:3526784 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429686 |
P |
From MGI |
||
| GO:0019221 |
cytokine-mediated signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019538 |
protein metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0021670 |
lateral ventricle development |
MGI:MGI:3763347 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0021849 |
neuroblast division in subventricular zone |
MGI:MGI:3763347 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030900 |
forebrain development |
MGI:MGI:2683798 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429686 |
P |
From MGI |
||
| GO:0034332 |
adherens junction organization |
MGI:MGI:3721043 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:107423 |
P |
From MGI |
||
| GO:0050769 |
positive regulation of neurogenesis |
MGI:MGI:2389562 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0050775 |
positive regulation of dendrite morphogenesis |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001029060 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Huang EJ et al. (2005) Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization. Genes Dev 19: 138-51 PubMed GONUTS page
- ↑ Zhong W et al. (1997) Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis. Development 124: 1887-97 PubMed GONUTS page
- ↑ 3.0 3.1 Li HS et al. (2003) Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron 40: 1105-18 PubMed GONUTS page
- ↑ 4.0 4.1 Petersen PH et al. (2002) Progenitor cell maintenance requires numb and numblike during mouse neurogenesis. Nature 419: 929-34 PubMed GONUTS page
- ↑ 5.0 5.1 Kuo CT et al. (2006) Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell 127: 1253-64 PubMed GONUTS page
- ↑ Rasin MR et al. (2007) Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci 10: 819-27 PubMed GONUTS page
