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MGI:Ntn1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ntn1 ( synonyms: Netrin-1 ) | |
| Protein Name(s) | netrin 1, | |
| External Links | ||
| MGI | MGI:105088 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001764 |
neuron migration |
MGI:MGI:3041654 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1927548 |
P |
From MGI |
||
| GO:0001764 |
neuron migration |
MGI:MGI:3607408 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1927548 |
P |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3829111 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005578 |
proteinaceous extracellular matrix |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:3807344 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3799386 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0053 |
P |
From MGI |
||
| GO:0007409 |
axonogenesis |
MGI:MGI:1861288 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007411 |
axon guidance |
MGI:MGI:1861288 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1927548 |
P |
From MGI |
||
| GO:0007411 |
axon guidance |
MGI:MGI:2181259 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007411 |
axon guidance |
MGI:MGI:2654974 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007411 |
axon guidance |
MGI:MGI:3616408 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1927548 |
P |
From MGI |
||
| GO:0007411 |
axon guidance |
MGI:MGI:3691957 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007411 |
axon guidance |
MGI:MGI:3758130 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1927548 |
P |
From MGI |
||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:3616408 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1927548 |
P |
From MGI |
||
| GO:0016337 |
cell-cell adhesion |
MGI:MGI:3617129 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1315205 |
P |
From MGI |
||
| GO:0030334 |
regulation of cell migration |
MGI:MGI:1353949 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030334 |
regulation of cell migration |
MGI:MGI:3616408 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1927548 |
P |
From MGI |
||
| GO:0030517 |
negative regulation of axon extension |
MGI:MGI:1353949 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030879 |
mammary gland development |
MGI:MGI:3799386 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97762 |
P |
From MGI |
||
| GO:0040023 |
establishment of nucleus localization |
MGI:MGI:2181259 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045773 |
positive regulation of axon extension |
MGI:MGI:1353949 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0060603 |
mammary gland duct morphogenesis |
MGI:MGI:3617129 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1315205 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Schwarting GA et al. (2004) Netrin 1-mediated chemoattraction regulates the migratory pathway of LHRH neurons. Eur J Neurosci 19: 11-20 PubMed GONUTS page
- ↑ Dillon AK et al. (2005) Molecular control of spinal accessory motor neuron/axon development in the mouse spinal cord. J Neurosci 25: 10119-30 PubMed GONUTS page
- ↑ Ly A et al. (2008) DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell 133: 1241-54 PubMed GONUTS page
- ↑ Manabe R et al. (2008) Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A 105: 12849-54 PubMed GONUTS page
- ↑ 5.0 5.1 Strizzi L et al. (2008) Netrin-1 can affect morphogenesis and differentiation of the mouse mammary gland. J Cell Physiol 216: 824-34 PubMed GONUTS page
- ↑ 6.0 6.1 Braisted JE et al. (2000) Netrin-1 promotes thalamic axon growth and is required for proper development of the thalamocortical projection. J Neurosci 20: 5792-801 PubMed GONUTS page
- ↑ 7.0 7.1 Causeret F et al. (2002) Slit antagonizes netrin-1 attractive effects during the migration of inferior olivary neurons. Dev Biol 246: 429-40 PubMed GONUTS page
- ↑ Charron F et al. (2003) The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell 113: 11-23 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Tsai HH et al. (2006) Netrin-1 is required for the normal development of spinal cord oligodendrocytes. J Neurosci 26: 1913-22 PubMed GONUTS page
- ↑ Okada A et al. (2006) Boc is a receptor for sonic hedgehog in the guidance of commissural axons. Nature 444: 369-73 PubMed GONUTS page
- ↑ Ren T et al. (2007) Diffusion tensor magnetic resonance imaging and tract-tracing analysis of Probst bundle structure in Netrin1- and DCC-deficient mice. J Neurosci 27: 10345-9 PubMed GONUTS page
- ↑ 12.0 12.1 Strickland P et al. (2006) Slit2 and netrin 1 act synergistically as adhesive cues to generate tubular bi-layers during ductal morphogenesis. Development 133: 823-32 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 Alcántara S et al. (2000) Netrin 1 acts as an attractive or as a repulsive cue for distinct migrating neurons during the development of the cerebellar system. Development 127: 1359-72 PubMed GONUTS page
