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MGI:Ntf5

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ntf5 ( synonyms: neurotrophin-4, NT-4, NT4, NT4/5, Ntf-5, Ntf4 )
Protein Name(s) neurotrophin 5,
External Links
MGI MGI:97381

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005102

receptor binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002072

F

From MGI

GO:0005166

neurotrophin p75 receptor binding

MGI:MGI:700192
PMID:8873083[1]

TAS: Traceable Author Statement

F

From MGI

GO:0005576

extracellular region

MGI:MGI:4412465
PMID:10908605[2]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P34131

C

From MGI

GO:0007402

ganglion mother cell fate determination

MGI:MGI:1354095
PMID:10681461[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1933845

P

From MGI

GO:0007616

long-term memory

MGI:MGI:1860699
PMID:10869436[4]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0008052

sensory organ boundary specification

MGI:MGI:1345538
PMID:10479455[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1933845

P

From MGI

GO:0008083

growth factor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0339

F

From MGI

GO:0008083

growth factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR020432

F

From MGI

GO:0008344

adult locomotory behavior

MGI:MGI:1354095
PMID:10681461[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1933845

P

From MGI

GO:0008544

epidermis development

MGI:MGI:1331591
PMID:9973328[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857233

P

From MGI

GO:0042490

mechanoreceptor differentiation

MGI:MGI:3505841
PMID:15376326[7]

IGI: Inferred from Genetic Interaction

MGI:MGI:1857136
MGI:MGI:1857232

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Ibáñez CF (1996) Neurotrophin-4: the odd one out in the neurotrophin family. Neurochem Res 21: 787-93 PubMed GONUTS page
  2. Zhang Y et al. (2000) Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation. J Neurosci 20: 5671-8 PubMed GONUTS page
  3. 3.0 3.1 Liebl DJ et al. (2000) Loss of brain-derived neurotrophic factor-dependent neural crest-derived sensory neurons in neurotrophin-4 mutant mice. Proc Natl Acad Sci U S A 97: 2297-302 PubMed GONUTS page
  4. Xie CW et al. (2000) Deficient long-term memory and long-lasting long-term potentiation in mice with a targeted deletion of neurotrophin-4 gene. Proc Natl Acad Sci U S A 97: 8116-21 PubMed GONUTS page
  5. Liebl DJ et al. (1999) NT4/5 mutant mice have deficiency in gustatory papillae and taste bud formation. Dev Biol 213: 378-89 PubMed GONUTS page
  6. Botchkarev VA et al. (1999) A new role for neurotrophins: involvement of brain-derived neurotrophic factor and neurotrophin-4 in hair cycle control. FASEB J 13: 395-410 PubMed GONUTS page
  7. Sedý J et al. (2004) Pacinian corpuscle development involves multiple Trk signaling pathways. Dev Dyn 231: 551-63 PubMed GONUTS page
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