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MGI:Nsf

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Nsf ( synonyms: N-ethylmaleimide sensitive factor, SKD2 )
Protein Name(s) N-ethylmaleimide sensitive fusion protein,
External Links
MGI MGI:104560

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000166

nucleotide binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

From MGI

GO:0001921

positive regulation of receptor recycling

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P46459

P

From MGI

GO:0005515

protein binding

MGI:MGI:4359331
PMID:19455133[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q62108

F

From MGI

GO:0005515

protein binding

MGI:MGI:4941068
PMID:21307259[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q5S006

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003959
InterPro:IPR003960

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:B4DFA2

C

From MGI

GO:0005795

Golgi stack

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88960

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P46459

C

From MGI

GO:0006200

ATP catabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88960

P

From MGI

GO:0006810

transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From MGI

GO:0006813

potassium ion transport

MGI:MGI:68293
PMID:8082782[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0008022

protein C-terminus binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88960

F

From MGI

GO:0008152

metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

P

From MGI

GO:0008152

metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

P

From MGI

GO:0014069

postsynaptic density

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88960

C

From MGI

GO:0015031

protein transport

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88960

P

From MGI

GO:0016192

vesicle-mediated transport

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88960

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0016887

ATPase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88960

F

From MGI

GO:0017111

nucleoside-triphosphatase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

From MGI

GO:0017137

Rab GTPase binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88960

F

From MGI

GO:0017157

regulation of exocytosis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88960

P

From MGI

GO:0019905

syntaxin binding

MGI:MGI:3029642
PMID:14755058[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0030165

PDZ domain binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P46459

F

From MGI

GO:0032403

protein complex binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P46459

F

From MGI

GO:0042623

ATPase activity, coupled

MGI:MGI:3050225
PMID:12832401[5]

IMP: Inferred from Mutant Phenotype

F

From MGI

GO:0043008

ATP-dependent protein binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88960

F

From MGI

GO:0043198

dendritic shaft

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O88960

C

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Fernández E et al. (2009) Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins. Mol Syst Biol 5: 269 PubMed GONUTS page
  2. Piccoli G et al. (2011) LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool. J Neurosci 31: 2225-37 PubMed GONUTS page
  3. Périer F et al. (1994) Identification of a novel mammalian member of the NSF/CDC48p/Pas1p/TBP-1 family through heterologous expression in yeast. FEBS Lett 351: 286-90 PubMed GONUTS page
  4. Hong HK et al. (2004) The gene for soluble N-ethylmaleimide sensitive factor attachment protein alpha is mutated in hydrocephaly with hop gait (hyh) mice. Proc Natl Acad Sci U S A 101: 1748-53 PubMed GONUTS page
  5. Widberg CH et al. (2003) Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation. J Biol Chem 278: 35093-101 PubMed GONUTS page
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