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MGI:Nsd1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Nsd1 ( synonyms: KMT3B ) | |
| Protein Name(s) | nuclear receptor-binding SET-domain protein 1, | |
| External Links | ||
| MGI | MGI:1276545 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001702 |
gastrulation with mouth forming second |
MGI:MGI:2664413 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2667262 |
P |
From MGI |
||
| GO:0003682 |
chromatin binding |
MGI:MGI:3057220 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003712 |
transcription cofactor activity |
MGI:MGI:1267129 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003712 |
transcription cofactor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3045680 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3045680 |
IC: Inferred by Curator |
GO:0000122 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:3772493 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1267129 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0008168 |
methyltransferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0489 |
F |
From MGI |
||
| GO:0008270 |
zinc ion binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0010452 |
histone H3-K36 methylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0018022 |
peptidyl-lysine methylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032259 |
methylation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0489 |
P |
From MGI |
||
| GO:0042054 |
histone methyltransferase activity |
MGI:MGI:2664413 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0046975 |
histone methyltransferase activity (H3-K36 specific) |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0050681 |
androgen receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:2001141 |
regulation of RNA biosynthetic process |
MGI:MGI:1267129 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Rayasam GV et al. (2003) NSD1 is essential for early post-implantation development and has a catalytically active SET domain. EMBO J 22: 3153-63 PubMed GONUTS page
- ↑ Wang L et al. (2004) Identification of potential nuclear reprogramming and differentiation factors by a novel selection method for cloning chromatin-binding proteins. Biochem Biophys Res Commun 325: 302-7 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Huang N et al. (1998) Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators. EMBO J 17: 3398-412 PubMed GONUTS page
- ↑ 4.0 4.1 Nielsen AL et al. (2004) Nizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motif. Mol Cell Biol 24: 5184-96 PubMed GONUTS page
- ↑ Edmunds JW et al. (2008) Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation. EMBO J 27: 406-20 PubMed GONUTS page
