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MGI:Nrp2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Nrp2 ( synonyms: NP-2, NP2, Npn-2, Npn2 )
Protein Name(s) neuropilin 2,
External Links
MGI MGI:1100492

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001755

neural crest cell migration

MGI:MGI:3613099
PMID:16319111[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2137037

P

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005515

protein binding

MGI:MGI:1346254
PMID:10520994[2]

IPI: Inferred from Physical Interaction

UniProtKB:P70206

F

From MGI

GO:0005886

plasma membrane

MGI:MGI:3050159
PMID:15239958[3]

IC: Inferred by Curator

GO:0017154

C

From MGI

GO:0007155

cell adhesion

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000421

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007399

nervous system development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From MGI

GO:0007411

axon guidance

MGI:MGI:3578029
PMID:15814794[4]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007507

heart development

MGI:MGI:3505728
PMID:12852851[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:106206

P

From MGI

GO:0008201

heparin binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0358

F

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016020

membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000998

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0017154

semaphorin receptor activity

MGI:MGI:3050159
PMID:15239958[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q62181

F

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0030424

axon

MGI:MGI:3574008
PMID:15677725[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0050919

negative chemotaxis

MGI:MGI:3578029
PMID:15814794[4]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0050919

negative chemotaxis

MGI:MGI:3613099
PMID:16319111[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1096347

P

From MGI

GO:0071526

semaphorin-plexin signaling pathway

MGI:MGI:3050159
PMID:15239958[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q62181

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Gammill LS et al. (2006) Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling. Development 133: 99-106 PubMed GONUTS page
  2. Takahashi T et al. (1999) Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. Cell 99: 59-69 PubMed GONUTS page
  3. 3.0 3.1 3.2 Gitler AD et al. (2004) PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Dev Cell 7: 107-16 PubMed GONUTS page
  4. 4.0 4.1 Suto F et al. (2005) Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance. J Neurosci 25: 3628-37 PubMed GONUTS page
  5. Gu C et al. (2003) Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev Cell 5: 45-57 PubMed GONUTS page
  6. Yoshihara S et al. (2005) Arx homeobox gene is essential for development of mouse olfactory system. Development 132: 751-62 PubMed GONUTS page
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