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MGI:Nrk

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Nrk ( synonyms: Nesk )
Protein Name(s) Nik related kinase,
External Links
MGI MGI:1351326

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:1349206
PMID:10559491[1]

ISA: Inferred from Sequence Alignment

EMBL:AF004934

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:1860727
PMID:10801798[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

From MGI

GO:0005083

small GTPase regulator activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001180

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441
InterPro:IPR002290

F

From MGI

GO:0005575

cellular component

MGI:MGI:2156816

ND: No biological Data available

C

From MGI

GO:0007256

activation of JNKK activity

MGI:MGI:1860727
PMID:10801798[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007567

parturition

MGI:MGI:5287920
PMID:21715335[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:5292103

P

From MGI

GO:0008285

negative regulation of cell proliferation

MGI:MGI:5287920
PMID:21715335[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:5292103

P

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0050790

regulation of catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001180

P

From MGI

GO:0060721

regulation of spongiotrophoblast cell proliferation

MGI:MGI:5287920
PMID:21715335[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:5292103

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Kanai-Azuma M et al. (1999) Nrk: a murine X-linked NIK (Nck-interacting kinase)-related kinase gene expressed in skeletal muscle. Mech Dev 89: 155-9 PubMed GONUTS page
  2. 2.0 2.1 Nakano K et al. (2000) NESK, a member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and is expressed during the late stages of embryogenesis. J Biol Chem 275: 20533-9 PubMed GONUTS page
  3. 3.0 3.1 3.2 Denda K et al. (2011) Nrk, an X-linked protein kinase in the germinal center kinase family, is required for placental development and fetoplacental induction of labor. J Biol Chem 286: 28802-10 PubMed GONUTS page
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