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MGI:Notch4

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Notch4 ( synonyms: Int-3, Int3, N4 )
Protein Name(s) Notch gene homolog 4 (Drosophila),
External Links
MGI MGI:107471

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001569

patterning of blood vessels

MGI:MGI:1934537
PMID:11344305[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0001763

morphogenesis of a branching structure

MGI:MGI:1934537
PMID:11344305[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0001886

endothelial cell morphogenesis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001002827

P

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005509

calcium ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001881
InterPro:IPR018097

F

From MGI

GO:0005515

protein binding

MGI:MGI:4418643
PMID:9389650[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q93794

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0007219

Notch signaling pathway

MGI:MGI:1934537
PMID:11344305[1]

TAS: Traceable Author Statement

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011656

P

From MGI

GO:0009790

embryo development

MGI:MGI:1934537
PMID:11344305[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0009986

cell surface

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99466

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016020

membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008297
InterPro:IPR000800

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011656

C

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0030154

cell differentiation

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000800
InterPro:IPR011656

P

From MGI

GO:0030879

mammary gland development

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99466

P

From MGI

GO:0045446

endothelial cell differentiation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001002827

P

From MGI

GO:0045602

negative regulation of endothelial cell differentiation

MGI:MGI:1934537
PMID:11344305[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0050793

regulation of developmental process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008297

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Uyttendaele H et al. (2001) Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium. Proc Natl Acad Sci U S A 98: 5643-8 PubMed GONUTS page
  2. Hubbard EJ et al. (1997) sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins. Genes Dev 11: 3182-93 PubMed GONUTS page
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