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MGI:Ngef

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ngef ( synonyms: ephexin, Tims2 )
Protein Name(s) neuronal guanine nucleotide exchange factor,
External Links
MGI MGI:1858414

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005085

guanyl-nucleotide exchange factor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0344

F

From MGI

GO:0005089

Rho guanyl-nucleotide exchange factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

F

From MGI

GO:0005515

protein binding

MGI:MGI:3696283
PMID:17143272[1]

IPI: Inferred from Physical Interaction

UniProtKB:P61809

F

From MGI

GO:0005543

phospholipid binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001849

F

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N5V2

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N5V2

C

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007399

nervous system development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From MGI

GO:0009987

cellular process

MGI:MGI:1355568
PMID:10777665[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0035023

regulation of Rho protein signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

P

From MGI

GO:0042995

cell projection

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0966

C

From MGI

GO:0043087

regulation of GTPase activity

MGI:MGI:3696283
PMID:17143272[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0046875

ephrin receptor binding

MGI:MGI:3696283
PMID:17143272[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q03137

F

From MGI

GO:0048013

ephrin receptor signaling pathway

MGI:MGI:3696283
PMID:17143272[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050790

regulation of catalytic activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0344

P

From MGI

GO:0050790

regulation of catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

P

From MGI

GO:0061002

negative regulation of dendritic spine morphogenesis

MGI:MGI:3696283
PMID:17143272[1]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Fu WY et al. (2007) Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism. Nat Neurosci 10: 67-76 PubMed GONUTS page
  2. Rodrigues NR et al. (2000) Characterization of Ngef, a novel member of the Dbl family of genes expressed predominantly in the caudate nucleus. Genomics 65: 53-61 PubMed GONUTS page
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