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MGI:Nfat5

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Nfat5 ( synonyms: nfatz, OREBP, TonEBP )
Protein Name(s) nuclear factor of activated T cells 5,
External Links
MGI MGI:1859333

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001816

cytokine production

MGI:MGI:3575325
PMID:15790681[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0003677

DNA binding

MGI:MGI:3575325
PMID:15790681[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:1858290
PMID:11233530[2]

ISS: Inferred from Sequence or Structural Similarity

F

From MGI

GO:0005634

nucleus

MGI:MGI:1859681
PMID:10860829[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:2389602
PMID:11934689[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:2389602
PMID:11934689[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1858290
PMID:11233530[2]

ISS: Inferred from Sequence or Structural Similarity

P

From MGI

GO:0010628

positive regulation of gene expression

MGI:MGI:4947150
PMID:21357543[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:2389602
PMID:11934689[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0070884

regulation of calcineurin-NFAT signaling cascade

MGI:MGI:3842072
PMID:19188439[6]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Bettelli E et al. (2005) Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A 102: 5138-43 PubMed GONUTS page
  2. 2.0 2.1 López-Rodríguez C et al. (1999) NF-AT5: the NF-AT family of transcription factors expands in a new direction. Cold Spring Harb Symp Quant Biol 64: 517-26 PubMed GONUTS page
  3. Pan S et al. (2000) NFATz: a novel rel similarity domain containing protein. Biochem Biophys Res Commun 272: 765-76 PubMed GONUTS page
  4. 4.0 4.1 4.2 Maouyo D et al. (2002) Mouse TonEBP-NFAT5: expression in early development and alternative splicing. Am J Physiol Renal Physiol 282: F802-9 PubMed GONUTS page
  5. Gimferrer I et al. (2011) Regulation of GATA-3 expression during CD4 lineage differentiation. J Immunol 186: 3892-8 PubMed GONUTS page
  6. Ikeda S et al. (2009) MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol 29: 2193-204 PubMed GONUTS page
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