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MGI:Nedd4l
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Nedd4l ( synonyms: Nedd4-2, Nedd4b ) | |
| Protein Name(s) | neural precursor cell expressed, developmentally down-regulated gene 4-like, | |
| External Links | ||
| MGI | MGI:1933754 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:4459044 |
PANTHER:PTHR11254 |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3713955 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0006464 |
protein modification process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0010038 |
response to metal ion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010766 |
negative regulation of sodium ion transport |
MGI:MGI:1929304 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0010766 |
negative regulation of sodium ion transport |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010766 |
negative regulation of sodium ion transport |
MGI:MGI:3761956 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016874 |
ligase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0436 |
F |
From MGI |
||
| GO:0016881 |
acid-amino acid ligase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0017080 |
sodium channel regulator activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0019871 |
sodium channel inhibitor activity |
MGI:MGI:1929304 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0042787 |
protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
MGI:MGI:4459044 |
PANTHER:PTHR11254 |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Sanchez-Perez A et al. (2007) GRK2 interacts with and phosphorylates Nedd4 and Nedd4-2. Biochem Biophys Res Commun 359: 611-5 PubMed GONUTS page
- ↑ 2.0 2.1 Kamynina E et al. (2001) A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel. FASEB J 15: 204-214 PubMed GONUTS page
- ↑ Lee IH et al. (2007) Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2. J Biol Chem 282: 29866-73 PubMed GONUTS page
acil |
np |
rsu |
