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MGI:Ndn
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ndn ( synonyms: Peg6 ) | |
| Protein Name(s) | necdin, | |
| External Links | ||
| MGI | MGI:97290 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001558 |
regulation of cell growth |
MGI:MGI:2181265 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0001764 |
neuron migration |
MGI:MGI:3582873 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2653048 |
P |
From MGI |
||
| GO:0003016 |
respiratory system process |
MGI:MGI:1345919 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2653045 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3027170 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3813780 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3828407 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3027170 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:2157602 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3027170 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001008558 |
C |
From MGI |
||
| GO:0005813 |
centrosome |
MGI:MGI:3530392 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:2157602 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:3027170 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:101941 |
P |
From MGI |
||
| GO:0006874 |
cellular calcium ion homeostasis |
MGI:MGI:2181265 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0007409 |
axonogenesis |
MGI:MGI:3530392 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2653048 |
P |
From MGI |
||
| GO:0007409 |
axonogenesis |
MGI:MGI:3582873 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2653048 |
P |
From MGI |
||
| GO:0007413 |
axonal fasciculation |
MGI:MGI:3582873 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2653048 |
P |
From MGI |
||
| GO:0007417 |
central nervous system development |
MGI:MGI:3530392 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2653048 |
P |
From MGI |
||
| GO:0007585 |
respiratory gaseous exchange |
MGI:MGI:2651969 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2653048 |
P |
From MGI |
||
| GO:0008347 |
glial cell migration |
MGI:MGI:3582873 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2653048 |
P |
From MGI |
||
| GO:0009791 |
post-embryonic development |
MGI:MGI:1345919 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2653045 |
P |
From MGI |
||
| GO:0019233 |
sensory perception of pain |
MGI:MGI:3586399 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3586988 |
P |
From MGI |
||
| GO:0040008 |
regulation of growth |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0341 |
P |
From MGI |
||
| GO:0042995 |
cell projection |
MGI:MGI:2157602 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043015 |
gamma-tubulin binding |
MGI:MGI:3530392 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0048011 |
nerve growth factor receptor signaling pathway |
MGI:MGI:3586399 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3586988 |
P |
From MGI |
||
| GO:0048666 |
neuron development |
MGI:MGI:3586399 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3586988 |
P |
From MGI |
||
| GO:0048676 |
axon extension involved in development |
MGI:MGI:3582873 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2653048 |
P |
From MGI |
||
| GO:0048871 |
multicellular organismal homeostasis |
MGI:MGI:1345919 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2653045 |
P |
From MGI |
||
| GO:0071514 |
genetic imprinting |
MGI:MGI:1345919 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2653045 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Sasaki A et al. (2002) A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein, Dlxin-1. J Biol Chem 277: 22541-6 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Pagliardini S et al. (2005) Developmental abnormalities of neuronal structure and function in prenatal mice lacking the prader-willi syndrome gene necdin. Am J Pathol 167: 175-91 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Gérard M et al. (1999) Disruption of the mouse necdin gene results in early post-natal lethality. Nat Genet 23: 199-202 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Kuwako K et al. (2004) Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor. J Biol Chem 279: 1703-12 PubMed GONUTS page
- ↑ Bush JR & Wevrick R (2008) The Prader-Willi syndrome protein necdin interacts with the E1A-like inhibitor of differentiation EID-1 and promotes myoblast differentiation. Differentiation 76: 994-1005 PubMed GONUTS page
- ↑ Kuwajima T et al. (2004) Necdin interacts with the Msx2 homeodomain protein via MAGE-D1 to promote myogenic differentiation of C2C12 cells. J Biol Chem 279: 40484-93 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Niinobe M et al. (2000) Cellular and subcellular localization of necdin in fetal and adult mouse brain. Dev Neurosci 22: 310-9 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 Lee S et al. (2005) Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth. Hum Mol Genet 14: 627-37 PubMed GONUTS page
- ↑ Ren J et al. (2003) Absence of Ndn, encoding the Prader-Willi syndrome-deleted gene necdin, results in congenital deficiency of central respiratory drive in neonatal mice. J Neurosci 23: 1569-73 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 Kuwako K et al. (2005) Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival. J Neurosci 25: 7090-9 PubMed GONUTS page
