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MGI:Nde1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Nde1 ( synonyms: mNudE ) | |
| Protein Name(s) | nuclear distribution gene E homolog 1 (A nidulans), | |
| External Links | ||
| MGI | MGI:1914453 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000132 |
establishment of mitotic spindle orientation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0000775 |
chromosome, centromeric region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0137 |
C |
From MGI |
||
| GO:0000776 |
kinetochore |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0001764 |
neuron migration |
MGI:MGI:1928549 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:1928549 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3583501 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4442527 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:3588829 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1932915 |
C |
From MGI |
||
| GO:0005694 |
chromosome |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0158 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0005813 |
centrosome |
MGI:MGI:1928549 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:3513966 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005815 |
microtubule organizing center |
MGI:MGI:1928549 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005819 |
spindle |
MGI:MGI:3513966 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0005874 |
microtubule |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0493 |
C |
From MGI |
||
| GO:0007020 |
microtubule nucleation |
MGI:MGI:1928549 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0007067 |
mitosis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0498 |
P |
From MGI |
||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007399 |
nervous system development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0524 |
P |
From MGI |
||
| GO:0007405 |
neuroblast proliferation |
MGI:MGI:3513966 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3514026 |
P |
From MGI |
||
| GO:0008017 |
microtubule binding |
MGI:MGI:3513966 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0019904 |
protein domain specific binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445799 |
F |
From MGI |
||
| GO:0021987 |
cerebral cortex development |
MGI:MGI:3805426 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:109520 |
P |
From MGI |
||
| GO:0021987 |
cerebral cortex development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0030900 |
forebrain development |
MGI:MGI:3513966 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3514026 |
P |
From MGI |
||
| GO:0031023 |
microtubule organizing center organization |
MGI:MGI:1928549 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0031616 |
spindle pole centrosome |
MGI:MGI:3513966 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042802 |
identical protein binding |
MGI:MGI:3513506 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0047496 |
vesicle transport along microtubule |
MGI:MGI:3588829 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1932915 |
P |
From MGI |
||
| GO:0051298 |
centrosome duplication |
MGI:MGI:3513966 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0051301 |
cell division |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0132 |
P |
From MGI |
||
| GO:0051303 |
establishment of chromosome localization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Feng Y et al. (2000) LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome. Neuron 28: 665-79 PubMed GONUTS page
- ↑ Soukoulis V et al. (2005) Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway. Proc Natl Acad Sci U S A 102: 8549-54 PubMed GONUTS page
- ↑ Hutchins JR et al. (2010) Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science 328: 593-9 PubMed GONUTS page
- ↑ 4.0 4.1 Sasaki S et al. (2005) Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality. Mol Cell Biol 25: 7812-27 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 Feng Y & Walsh CA (2004) Mitotic spindle regulation by Nde1 controls cerebral cortical size. Neuron 44: 279-93 PubMed GONUTS page
- ↑ Pawlisz AS et al. (2008) Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination. Hum Mol Genet 17: 2441-55 PubMed GONUTS page
- ↑ Cybulska-Klosowicz A et al. (2004) Impaired learning-dependent cortical plasticity in Huntington's disease transgenic mice. Neurobiol Dis 17: 427-34 PubMed GONUTS page
