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MGI:Nck2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Nck2 ( synonyms: Grb4, NCKbeta ) | |
| Protein Name(s) | non-catalytic region of tyrosine kinase adaptor protein 2, | |
| External Links | ||
| MGI | MGI:1306821 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0256 |
C |
From MGI |
||
| GO:0006417 |
regulation of translation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0810 |
P |
From MGI |
||
| GO:0007015 |
actin filament organization |
MGI:MGI:2662675 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2667153 |
P |
From MGI |
||
| GO:0012506 |
vesicle membrane |
MGI:MGI:2387810 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016477 |
cell migration |
MGI:MGI:2662675 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2667153 |
P |
From MGI |
||
| GO:0030032 |
lamellipodium assembly |
MGI:MGI:2664446 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2667153 |
P |
From MGI |
||
| GO:0030838 |
positive regulation of actin filament polymerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042102 |
positive regulation of T cell proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Van Impe K et al. (2003) The Nucleo-cytoplasmic actin-binding protein CapG lacks a nuclear export sequence present in structurally related proteins. J Biol Chem 278: 17945-52 PubMed GONUTS page
- ↑ Benesch S et al. (2002) Phosphatidylinositol 4,5-biphosphate (PIP2)-induced vesicle movement depends on N-WASP and involves Nck, WIP, and Grb2. J Biol Chem 277: 37771-6 PubMed GONUTS page
- ↑ Bladt F et al. (2003) The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network. Mol Cell Biol 23: 4586-97 PubMed GONUTS page
