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MGI:Nbr1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Nbr1 | |
| Protein Name(s) | neighbor of Brca1 gene 1, | |
| External Links | ||
| MGI | MGI:108498 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000407 |
pre-autophagosomal structure |
MGI:MGI:4880808 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3837054 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0005764 |
lysosome |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0458 |
C |
From MGI |
||
| GO:0005770 |
late endosome |
MGI:MGI:3837054 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0008270 |
zinc ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016236 |
macroautophagy |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030500 |
regulation of bone mineralization |
MGI:MGI:4818844 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0031410 |
cytoplasmic vesicle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0968 |
C |
From MGI |
||
| GO:0032872 |
regulation of stress-activated MAPK cascade |
MGI:MGI:4818844 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043130 |
ubiquitin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045668 |
negative regulation of osteoblast differentiation |
MGI:MGI:4818844 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0051019 |
mitogen-activated protein kinase binding |
MGI:MGI:4818844 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0051259 |
protein oligomerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
colocalizes_with |
GO:0005776 |
autophagic vacuole |
MGI:MGI:4818844 |
IDA: Inferred from Direct Assay |
C |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Itakura E & Mizushima N (2011) p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding. J Cell Biol 192: 17-27 PubMed GONUTS page
- ↑ 2.0 2.1 Kirkin V et al. (2009) A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol Cell 33: 505-16 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Whitehouse CA et al. (2010) Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity. Proc Natl Acad Sci U S A 107: 12913-8 PubMed GONUTS page
