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MGI:Napa
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Napa ( synonyms: a-SNAP, hyh, RA81, SNAPA, SNARE ) | |
| Protein Name(s) | N-ethylmaleimide sensitive fusion protein attachment protein alpha, | |
| External Links | ||
| MGI | MGI:104563 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000149 |
SNARE binding |
MGI:MGI:76787 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4879076 |
IPI: Inferred from Physical Interaction |
UniProtKB:P63044 |
F |
From MGI |
||
| GO:0005622 |
intracellular |
MGI:MGI:3029642 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856610 |
C |
From MGI |
||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006886 |
intracellular protein transport |
MGI:MGI:3029642 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856610 |
P |
From MGI |
||
| GO:0007420 |
brain development |
MGI:MGI:2157723 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856610 |
P |
From MGI |
||
| GO:0010807 |
regulation of synaptic vesicle priming |
MGI:MGI:4879076 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:104562 |
P |
From MGI |
||
| GO:0015031 |
protein transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0653 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016192 |
vesicle-mediated transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0931 |
P |
From MGI |
||
| GO:0019905 |
syntaxin binding |
MGI:MGI:3029642 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0030182 |
neuron differentiation |
MGI:MGI:3033551 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856610 |
P |
From MGI |
||
| GO:0035249 |
synaptic transmission, glutamatergic |
MGI:MGI:4879076 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:104562 |
P |
From MGI |
||
| GO:0035494 |
SNARE complex disassembly |
MGI:MGI:4879076 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:104562 |
P |
From MGI |
||
| GO:0045176 |
apical protein localization |
MGI:MGI:3033551 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856610 |
P |
From MGI |
||
| GO:0070044 |
synaptobrevin 2-SNAP-25-syntaxin-1a complex |
MGI:MGI:4879076 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0070044 |
synaptobrevin 2-SNAP-25-syntaxin-1a complex |
MGI:MGI:76787 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 McMahon HT et al. (1995) Complexins: cytosolic proteins that regulate SNAP receptor function. Cell 83: 111-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Burgalossi A et al. (2010) SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming. Neuron 68: 473-87 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Hong HK et al. (2004) The gene for soluble N-ethylmaleimide sensitive factor attachment protein alpha is mutated in hydrocephaly with hop gait (hyh) mice. Proc Natl Acad Sci U S A 101: 1748-53 PubMed GONUTS page
- ↑ Jiménez AJ et al. (2001) A programmed ependymal denudation precedes congenital hydrocephalus in the hyh mutant mouse. J Neuropathol Exp Neurol 60: 1105-19 PubMed GONUTS page
- ↑ 5.0 5.1 Chae TH et al. (2004) The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate. Nat Genet 36: 264-70 PubMed GONUTS page
