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MGI:Myog
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Myog ( synonyms: bHLHc3, myo ) | |
| Protein Name(s) | myogenin, | |
| External Links | ||
| MGI | MGI:97276 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000987 |
core promoter proximal region sequence-specific DNA binding |
MGI:MGI:4819086 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0001503 |
ossification |
MGI:MGI:79097 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:97252 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:1888583 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:2651740 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:3027696 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:3588628 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2651740 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003705 |
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity |
MGI:MGI:75196 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3624056 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3840749 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:75196 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
MGI:MGI:75196 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007517 |
muscle organ development |
MGI:MGI:79097 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97252 |
P |
From MGI |
||
| GO:0007519 |
skeletal muscle tissue development |
MGI:MGI:3027696 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007519 |
skeletal muscle tissue development |
MGI:MGI:75196 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:3763850 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:1888583 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:2651740 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4819086 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:99532 |
P |
From MGI |
||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:82422 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048741 |
skeletal muscle fiber development |
MGI:MGI:62381 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857667 |
P |
From MGI |
||
| GO:0071285 |
cellular response to lithium ion |
MGI:MGI:3581945 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0071363 |
cellular response to growth factor stimulus |
MGI:MGI:3512872 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Jung SY & Ko YG (2010) TRIM72, a novel negative feedback regulator of myogenesis, is transcriptionally activated by the synergism of MyoD (or myogenin) and MEF2. Biochem Biophys Res Commun 396: 238-45 PubMed GONUTS page
- ↑ 2.0 2.1 Wang Y et al. (1996) Functional redundancy of the muscle-specific transcription factors Myf5 and myogenin. Nature 379: 823-5 PubMed GONUTS page
- ↑ 3.0 3.1 Biederer CH et al. (2000) The basic helix-loop-helix transcription factors myogenin and Id2 mediate specific induction of caveolin-3 gene expression during embryonic development. J Biol Chem 275: 26245-51 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Meech R et al. (2003) The homeodomain protein Barx2 promotes myogenic differentiation and is regulated by myogenic regulatory factors. J Biol Chem 278: 8269-78 PubMed GONUTS page
- ↑ 5.0 5.1 Günther S et al. (2004) VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation. Nucleic Acids Res 32: 791-802 PubMed GONUTS page
- ↑ Nakagawa O et al. (2005) Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2. Genes Dev 19: 2066-77 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Weintraub H et al. (1991) The myoD gene family: nodal point during specification of the muscle cell lineage. Science 251: 761-6 PubMed GONUTS page
- ↑ Bajanca F et al. (2006) Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo. Development 133: 1635-44 PubMed GONUTS page
- ↑ Lagirand-Cantaloube J et al. (2009) Inhibition of atrogin-1/MAFbx mediated MyoD proteolysis prevents skeletal muscle atrophy in vivo. PLoS One 4: e4973 PubMed GONUTS page
- ↑ Davie JK et al. (2007) Target gene selectivity of the myogenic basic helix-loop-helix transcription factor myogenin in embryonic muscle. Dev Biol 311: 650-64 PubMed GONUTS page
- ↑ Hofmann TJ & Cole MD (1996) The TAL1/Scl basic helix-loop-helix protein blocks myogenic differentiation and E-box dependent transactivation. Oncogene 13: 617-24 PubMed GONUTS page
- ↑ Hasty P et al. (1993) Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene. Nature 364: 501-6 PubMed GONUTS page
- ↑ Vertino AM et al. (2005) Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts. Mol Biol Cell 16: 2039-48 PubMed GONUTS page
- ↑ Viñals F & Ventura F (2004) Myogenin protein stability is decreased by BMP-2 through a mechanism implicating Id1. J Biol Chem 279: 45766-72 PubMed GONUTS page
