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MGI:Myh7

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Myh7 ( synonyms: B-MHC, beta-MHC, MYH-beta/slow, Myhc-b, MyHC-I, Myhcb )
Protein Name(s) myosin, heavy polypeptide 7, cardiac muscle, beta,
External Links
MGI MGI:2155600

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000146

microfilament motor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P02564

F

From MGI

GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0001725

stress fiber

MGI:MGI:4936789
PMID:21126233[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0002027

regulation of heart rate

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12883

P

From MGI

GO:0003774

motor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001609
InterPro:IPR004009
InterPro:IPR002928

F

From MGI

GO:0003779

actin binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0009

F

From MGI

GO:0005516

calmodulin binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0112

F

From MGI

GO:0005524

ATP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P02564

F

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:F5H4L2

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:F5H4L2

C

From MGI

GO:0005859

muscle myosin complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P02564

C

From MGI

GO:0005925

focal adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:F5H4L2

C

From MGI

GO:0006200

ATP catabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P02564

P

From MGI

GO:0006200

ATP catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12883

P

From MGI

GO:0006936

muscle contraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P02564

P

From MGI

GO:0006936

muscle contraction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12883

P

From MGI

GO:0007512

adult heart development

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12883

P

From MGI

GO:0008152

metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001609
InterPro:IPR004009
InterPro:IPR002928

P

From MGI

GO:0008307

structural constituent of muscle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12883

F

From MGI

GO:0016459

myosin complex

MGI:MGI:1195842
PMID:8482409[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016459

myosin complex

MGI:MGI:1327483
PMID:9884344[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016887

ATPase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P02564

F

From MGI

GO:0016887

ATPase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12883

F

From MGI

GO:0030016

myofibril

MGI:MGI:1327483
PMID:9884344[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030018

Z disc

MGI:MGI:4936789
PMID:21126233[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030049

muscle filament sliding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12883

P

From MGI

GO:0030898

actin-dependent ATPase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12883

F

From MGI

GO:0032982

myosin filament

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12883

C

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P02564

F

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P02564

F

From MGI

GO:0055010

ventricular cardiac muscle tissue morphogenesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12883

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Park I et al. (2011) Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity. Biochem J 434: 171-80 PubMed GONUTS page
  2. Murakami N et al. (1993) Changes in expression of nonmuscle myosin heavy chain isoforms during muscle and nonmuscle tissue development. Dev Biol 157: 19-27 PubMed GONUTS page
  3. 3.0 3.1 Fatkin D et al. (1999) Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene. J Clin Invest 103: 147-53 PubMed GONUTS page
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