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MGI:Myb

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Myb ( synonyms: c-myb )
Protein Name(s) myeloblastosis oncogene,
External Links
MGI MGI:97249

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000082

G1/S transition of mitotic cell cycle

MGI:MGI:2667242
PMID:12660151[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P10242

P

From MGI

GO:0001701

in utero embryonic development

MGI:MGI:1346939
PMID:10523863[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2662859

P

From MGI

GO:0001701

in utero embryonic development

MGI:MGI:3763573
PMID:17927961[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3047076

P

From MGI

GO:0003677

DNA binding

MGI:MGI:2664666
PMID:12628004[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2664666
PMID:12628004[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2667242
PMID:12660151[1]

IMP: Inferred from Mutant Phenotype

F

From MGI

GO:0005515

protein binding

MGI:MGI:3040155
PMID:15082531[5]

IPI: Inferred from Physical Interaction

UniProtKB:Q9QZR5

F

From MGI

GO:0005634

nucleus

MGI:MGI:2664666
PMID:12628004[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:3653971
PMID:16847320[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:80263
PMID:8302594[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006338

chromatin remodeling

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P10242

P

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2664666
PMID:12628004[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2667242
PMID:12660151[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0006816

calcium ion transport

MGI:MGI:2667242
PMID:12660151[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0010468

regulation of gene expression

MGI:MGI:1346939
PMID:10523863[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2662859

P

From MGI

GO:0030183

B cell differentiation

MGI:MGI:3763573
PMID:17927961[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3047076

P

From MGI

GO:0045624

positive regulation of T-helper cell differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P10242

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P10242

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P10242

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3039314
PMID:15094381[8]

IGI: Inferred from Genetic Interaction

MGI:MGI:1338823
MGI:MGI:97489
MGI:MGI:96770

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P10242

P

From MGI

GO:0048538

thymus development

MGI:MGI:3763573
PMID:17927961[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3047076

P

From MGI

GO:0048566

embryonic digestive tract development

MGI:MGI:1346939
PMID:10523863[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2662859

P

From MGI

GO:0048872

homeostasis of number of cells

MGI:MGI:3763573
PMID:17927961[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3047076

P

From MGI

GO:0051571

positive regulation of histone H3-K4 methylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P10242

P

From MGI

GO:0051574

positive regulation of histone H3-K9 methylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P10242

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Afroze T et al. (2003) Calcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycle. Am J Physiol Cell Physiol 285: C88-95 PubMed GONUTS page
  2. 2.0 2.1 2.2 Zorbas M et al. (1999) c-Myb is critical for murine colon development. Oncogene 18: 5821-30 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Park ES et al. (2007) Early embryonic lethality caused by targeted disruption of the TRAF-interacting protein (TRIP) gene. Biochem Biophys Res Commun 363: 971-7 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Matre V et al. (2003) The human neuroendocrine thyrotropin-releasing hormone receptor promoter is activated by the haematopoietic transcription factor c-Myb. Biochem J 372: 851-9 PubMed GONUTS page
  5. Kanei-Ishii C et al. (2004) Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK. Genes Dev 18: 816-29 PubMed GONUTS page
  6. Ferretti E et al. (2006) Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype. Mol Cell Biol 26: 5650-62 PubMed GONUTS page
  7. Favier D & Gonda TJ (1994) Detection of proteins that bind to the leucine zipper motif of c-Myb. Oncogene 9: 305-11 PubMed GONUTS page
  8. Wu CX et al. (2004) Activation of mouse RAG-2 promoter by Myc-associated zinc finger protein. Biochem Biophys Res Commun 317: 1096-102 PubMed GONUTS page
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