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MGI:Mtss1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mtss1 ( synonyms: MIM )
Protein Name(s) metastasis suppressor 1,
External Links
MGI MGI:2384818

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003779

actin binding

MGI:MGI:2651741
PMID:12482861[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003785

actin monomer binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43312

F

From MGI

GO:0005102

receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43312

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:2651741
PMID:12482861[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005856

cytoskeleton

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From MGI

GO:0007015

actin filament organization

MGI:MGI:2651741
PMID:12482861[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007165

signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013606

P

From MGI

GO:0007399

nervous system development

MGI:MGI:2651741
PMID:12482861[1]

NAS: Non-traceable Author Statement

P

From MGI

GO:0007517

muscle organ development

MGI:MGI:2651741
PMID:12482861[1]

NAS: Non-traceable Author Statement

P

From MGI

GO:0008093

cytoskeletal adaptor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013606

F

From MGI

GO:0015629

actin cytoskeleton

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43312

C

From MGI

GO:0017124

SH3 domain binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013606

F

From MGI

GO:0030041

actin filament polymerization

MGI:MGI:2651741
PMID:12482861[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0046847

filopodium assembly

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013606

P

From MGI

GO:0050680

negative regulation of epithelial cell proliferation

MGI:MGI:4440396
PMID:20181743[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0061333

renal tubule morphogenesis

MGI:MGI:4440396
PMID:20181743[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0071498

cellular response to fluid shear stress

MGI:MGI:4440396
PMID:20181743[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0072102

glomerulus morphogenesis

MGI:MGI:4440396
PMID:20181743[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0072160

nephron tubule epithelial cell differentiation

MGI:MGI:4440396
PMID:20181743[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:2001013

epithelial cell proliferation involved in renal tubule morphogenesis

MGI:MGI:4440396
PMID:20181743[2]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Mattila PK et al. (2003) Mouse MIM, a tissue-specific regulator of cytoskeletal dynamics, interacts with ATP-actin monomers through its C-terminal WH2 domain. J Biol Chem 278: 8452-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Xia S et al. (2010) Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts. Development 137: 1075-84 PubMed GONUTS page
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