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MGI:Mtdh

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mtdh ( synonyms: 3D3/Lyric, AEG-1, D8Bwg1112e, Lyric )
Protein Name(s) metadherin,
External Links
MGI MGI:1914404

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

P

From MGI

GO:0001085

RNA polymerase II transcription factor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

F

From MGI

GO:0003713

transcription coactivator activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

F

From MGI

GO:0005515

protein binding

MGI:MGI:4352957
PMID:19433866[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9CYH6

F

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

C

From MGI

GO:0005730

nucleolus

MGI:MGI:3032820
PMID:14980505[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005730

nucleolus

MGI:MGI:4352957
PMID:19433866[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005730

nucleolus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:3032820
PMID:14980505[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:E5RJU9

C

From MGI

GO:0005789

endoplasmic reticulum membrane

MGI:MGI:4352957
PMID:19433866[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005923

tight junction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_596889

C

From MGI

GO:0010508

positive regulation of autophagy

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016324

apical plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_596889

C

From MGI

GO:0016604

nuclear body

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

C

From MGI

GO:0030054

cell junction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0965

C

From MGI

GO:0031663

lipopolysaccharide-mediated signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

P

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

P

From MGI

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

P

From MGI

GO:0045766

positive regulation of angiogenesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

P

From MGI

GO:0046581

intercellular canaliculus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_596889

C

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:3032820
PMID:14980505[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_596889

C

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

C

From MGI

GO:0051059

NF-kappaB binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

F

From MGI

GO:0051092

positive regulation of NF-kappaB transcription factor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

P

From MGI

GO:0051897

positive regulation of protein kinase B signaling cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q86UE4

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Carnemolla A et al. (2009) Rrs1 is involved in endoplasmic reticulum stress response in Huntington disease. J Biol Chem 284: 18167-73 PubMed GONUTS page
  2. 2.0 2.1 2.2 Sutherland HG et al. (2004) 3D3/lyric: a novel transmembrane protein of the endoplasmic reticulum and nuclear envelope, which is also present in the nucleolus. Exp Cell Res 294: 94-105 PubMed GONUTS page
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