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MGI:Mta2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Mta2 ( synonyms: mmta2, Mta1l1 ) | |
| Protein Name(s) | metastasis-associated gene family, member 2, | |
| External Links | ||
| MGI | MGI:1346340 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000118 |
histone deacetylase complex |
MGI:MGI:1342369 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:2154000 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0000989 |
transcription factor binding transcription factor activity |
MGI:MGI:4844227 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0001085 |
RNA polymerase II transcription factor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004407 |
histone deacetylase activity |
MGI:MGI:1342369 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2178733 |
IPI: Inferred from Physical Interaction |
UniProtKB:Q60973 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:2683041 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3619832 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4422158 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4844227 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2154000 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3619832 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005667 |
transcription factor complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006323 |
DNA packaging |
MGI:MGI:1342369 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006338 |
chromatin remodeling |
MGI:MGI:2683041 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008270 |
zinc ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016575 |
histone deacetylation |
MGI:MGI:1342369 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016581 |
NuRD complex |
MGI:MGI:2683041 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016581 |
NuRD complex |
MGI:MGI:3619832 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0016581 |
NuRD complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016585 |
chromatin remodeling complex |
MGI:MGI:1342369 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0044212 |
transcription regulatory region DNA binding |
MGI:MGI:4844227 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4844227 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:2154000 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Zhang Y et al. (1999) Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. Genes Dev 13: 1924-35 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Matsusue K et al. (2001) Characterization of mouse metastasis-associated gene 2: genomic structure, nuclear localization signal, and alternative potentials as transcriptional activator and repressor. DNA Cell Biol 20: 603-11 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Hwang SS et al. (2010) GATA-binding protein-3 regulates T helper type 2 cytokine and ifng loci through interaction with metastasis-associated protein 2. Immunology 131: 50-8 PubMed GONUTS page
- ↑ Kiefer SM et al. (2002) Murine Sall1 represses transcription by recruiting a histone deacetylase complex. J Biol Chem 277: 14869-76 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Zoltewicz JS et al. (2004) Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis. Development 131: 3-14 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Kaji K et al. (2006) The NuRD component Mbd3 is required for pluripotency of embryonic stem cells. Nat Cell Biol 8: 285-92 PubMed GONUTS page
- ↑ Snow JW & Orkin SH (2009) Translational isoforms of FOG1 regulate GATA1-interacting complexes. J Biol Chem 284: 29310-9 PubMed GONUTS page