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MGI:Mpo

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mpo
Protein Name(s) myeloperoxidase,
External Links
MGI MGI:97137

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001878

response to yeast

MGI:MGI:1333719
PMID:10085024[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176344

P

From MGI

GO:0002149

hypochlorous acid biosynthetic process

MGI:MGI:1333719
PMID:10085024[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176344

P

From MGI

GO:0002679

respiratory burst involved in defense response

MGI:MGI:1333719
PMID:10085024[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176344

P

From MGI

GO:0004601

peroxidase activity

MGI:MGI:1333719
PMID:10085024[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004601

peroxidase activity

MGI:MGI:1333719
PMID:10085024[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176344

F

From MGI

GO:0004601

peroxidase activity

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P05164

F

From MGI

GO:0004601

peroxidase activity

MGI:MGI:2157179
PMID:11792727[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004601

peroxidase activity

MGI:MGI:2179579
PMID:11980719[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004601

peroxidase activity

MGI:MGI:3044469
PMID:15159534[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004601

peroxidase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001100506

F

From MGI

GO:0005615

extracellular space

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001100506

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05164

C

From MGI

GO:0005625

soluble fraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001100506

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:2682130
PMID:14651853[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005764

lysosome

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0458

C

From MGI

GO:0006979

response to oxidative stress

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001100506

P

From MGI

GO:0008201

heparin binding

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P05164

F

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

F

From MGI

GO:0019430

removal of superoxide radicals

MGI:MGI:1333719
PMID:10085024[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176344

P

From MGI

GO:0020037

heme binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR010255
InterPro:IPR002007
InterPro:IPR019791

F

From MGI

GO:0030141

secretory granule

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P05164

C

From MGI

GO:0034374

low-density lipoprotein particle remodeling

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05164

P

From MGI

GO:0042744

hydrogen peroxide catabolic process

MGI:MGI:1333719
PMID:10085024[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0042744

hydrogen peroxide catabolic process

MGI:MGI:1333719
PMID:10085024[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176344

P

From MGI

GO:0042744

hydrogen peroxide catabolic process

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P05164

P

From MGI

GO:0044130

negative regulation of growth of symbiont in host

MGI:MGI:1333719
PMID:10085024[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176344

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0050832

defense response to fungus

MGI:MGI:1333719
PMID:10085024[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176344

P

From MGI

GO:0055114

oxidation-reduction process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

P

From MGI

GO:0055114

oxidation-reduction process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05164

P

From MGI

NOT

GO:0050830

defense response to Gram-positive bacterium

MGI:MGI:1333719
PMID:10085024[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2176344

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Aratani Y et al. (1999) Severe impairment in early host defense against Candida albicans in mice deficient in myeloperoxidase. Infect Immun 67: 1828-36 PubMed GONUTS page
  2. Hogenboom S et al. (2002) Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis. J Lipid Res 43: 90-8 PubMed GONUTS page
  3. Dahl R et al. (2002) Spi-B can functionally replace PU.1 in myeloid but not lymphoid development. EMBO J 21: 2220-30 PubMed GONUTS page
  4. Anton PM et al. (2004) Corticotropin-releasing hormone (CRH) requirement in Clostridium difficile toxin A-mediated intestinal inflammation. Proc Natl Acad Sci U S A 101: 8503-8 PubMed GONUTS page
  5. Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
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