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MGI:Mpg
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Mpg ( synonyms: 3-methyladenine DNA glycosylase, Aag, alkylpurine-DNA-N-glycosylase, APNG, Mid1 ) | |
| Protein Name(s) | N-methylpurine-DNA glycosylase, | |
| External Links | ||
| MGI | MGI:97073 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003824 |
catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003905 |
alkylbase DNA N-glycosylase activity |
MGI:MGI:2181327 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148592 |
F |
From MGI |
||
| GO:0003905 |
alkylbase DNA N-glycosylase activity |
MGI:MGI:3028824 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2675730 |
F |
From MGI |
||
| GO:0003905 |
alkylbase DNA N-glycosylase activity |
MGI:MGI:52437 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0006281 |
DNA repair |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From MGI |
||
| GO:0006284 |
base-excision repair |
MGI:MGI:2181327 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148592 |
P |
From MGI |
||
| GO:0006284 |
base-excision repair |
MGI:MGI:3028824 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2675730 |
P |
From MGI |
||
| GO:0006974 |
response to DNA damage stimulus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0227 |
P |
From MGI |
||
| GO:0008725 |
DNA-3-methyladenine glycosylase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0043916 |
DNA-7-methylguanine glycosylase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0052821 |
DNA-7-methyladenine glycosylase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0052822 |
DNA-3-methylguanine glycosylase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Hang B et al. (1997) Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine. Proc Natl Acad Sci U S A 94: 12869-74 PubMed GONUTS page
- ↑ 2.0 2.1 Ham AJ et al. (2004) New immunoaffinity-LC-MS/MS methodology reveals that Aag null mice are deficient in their ability to clear 1,N6-etheno-deoxyadenosine DNA lesions from lung and liver in vivo. DNA Repair (Amst) 3: 257-65 PubMed GONUTS page
- ↑ Engelward BP et al. (1993) Cloning and characterization of a mouse 3-methyladenine/7-methyl-guanine/3-methylguanine DNA glycosylase cDNA whose gene maps to chromosome 11. Carcinogenesis 14: 175-81 PubMed GONUTS page
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d cont. |
d cont.hnr |
