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MGI:Mnx1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mnx1 ( synonyms: HB9, Hlxb9, MNR2 )
Protein Name(s) motor neuron and pancreas homeobox 1,
External Links
MGI MGI:109160

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001764

neuron migration

MGI:MGI:1344237
PMID:10482234[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182358
MGI:MGI:2182361
MGI:MGI:2182363

P

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238
UniProtKB-KW:KW-0371

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR009057

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

F

From MGI

GO:0005634

nucleus

MGI:MGI:3695349
PMID:17042795[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970
InterPro:IPR001356

P

From MGI

GO:0008045

motor axon guidance

MGI:MGI:1344237
PMID:10482234[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182358
MGI:MGI:2182361
MGI:MGI:2182363

P

From MGI

GO:0009791

post-embryonic development

MGI:MGI:1344237
PMID:10482234[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182358
MGI:MGI:2182361
MGI:MGI:2182363

P

From MGI

GO:0021520

spinal cord motor neuron cell fate specification

MGI:MGI:1344237
PMID:10482234[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182358
MGI:MGI:2182361
MGI:MGI:2182363

P

From MGI

GO:0021675

nerve development

MGI:MGI:1935007
PMID:11395002[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2447793

P

From MGI

GO:0021904

dorsal/ventral neural tube patterning

MGI:MGI:3806189
PMID:18590716[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0021953

central nervous system neuron differentiation

MGI:MGI:1344237
PMID:10482234[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182358
MGI:MGI:2182361
MGI:MGI:2182363

P

From MGI

GO:0030182

neuron differentiation

MGI:MGI:1935007
PMID:11395002[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2447793

P

From MGI

GO:0031016

pancreas development

MGI:MGI:1344214
PMID:10471501[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182358

P

From MGI

GO:0031018

endocrine pancreas development

MGI:MGI:1344214
PMID:10471501[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182358

P

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970
InterPro:IPR001356

F

From MGI

GO:0048667

cell morphogenesis involved in neuron differentiation

MGI:MGI:1344237
PMID:10482234[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182358
MGI:MGI:2182361
MGI:MGI:2182363

P

From MGI

GO:0048812

neuron projection morphogenesis

MGI:MGI:1344237
PMID:10482234[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182358
MGI:MGI:2182361
MGI:MGI:2182363

P

From MGI

GO:0060539

diaphragm development

MGI:MGI:1344237
PMID:10482234[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182358
MGI:MGI:2182361
MGI:MGI:2182363

P

From MGI

GO:0060541

respiratory system development

MGI:MGI:1344237
PMID:10482234[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182358
MGI:MGI:2182361
MGI:MGI:2182363

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Arber S et al. (1999) Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron 23: 659-74 PubMed GONUTS page
  2. Winseck AK & Oppenheim RW (2006) An in vivo analysis of Schwann cell programmed cell death in embryonic mice: the role of axons, glial growth factor, and the pro-apoptotic gene Bax. Eur J Neurosci 24: 2105-17 PubMed GONUTS page
  3. 3.0 3.1 Yang X et al. (2001) Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation. Neuron 30: 399-410 PubMed GONUTS page
  4. Cho A et al. (2008) FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism. Dev Biol 321: 27-39 PubMed GONUTS page
  5. 5.0 5.1 Li H et al. (1999) Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9. Nat Genet 23: 67-70 PubMed GONUTS page
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