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MGI:Mmp9

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mmp9 ( synonyms: B/MMP9, Clg4b, Gel B, Gelatinase B, MMP-9 )
Protein Name(s) matrix metallopeptidase 9,
External Links
MGI MGI:97011

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001501

skeletal system development

MGI:MGI:3589495
PMID:15800063[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:96778

P

From MGI

GO:0001501

skeletal system development

MGI:MGI:3589495
PMID:15800063[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1932294

P

From MGI

GO:0001968

fibronectin binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

F

From MGI

GO:0004222

metalloendopeptidase activity

MGI:MGI:1096214
PMID:9291580[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004222

metalloendopeptidase activity

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P14780

F

From MGI

GO:0004222

metalloendopeptidase activity

MGI:MGI:3027355
PMID:14707083[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004222

metalloendopeptidase activity

MGI:MGI:3607885
PMID:12419962[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0272

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14780

C

From MGI

GO:0006508

proteolysis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

P

From MGI

GO:0006508

proteolysis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14780

P

From MGI

GO:0006979

response to oxidative stress

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

P

From MGI

GO:0007566

embryo implantation

MGI:MGI:3813178
PMID:18556655[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0008152

metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002477

P

From MGI

GO:0008233

peptidase activity

MGI:MGI:3589495
PMID:15800063[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0008237

metallopeptidase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

F

From MGI

GO:0008270

zinc ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001818
InterPro:IPR021190
InterPro:IPR021158
InterPro:IPR006026

F

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0019087

transformation of host cell by virus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

P

From MGI

GO:0030198

extracellular matrix organization

MGI:MGI:3589495
PMID:15800063[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:96778

P

From MGI

GO:0030198

extracellular matrix organization

MGI:MGI:3589495
PMID:15800063[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1932294

P

From MGI

GO:0030574

collagen catabolic process

MGI:MGI:1096214
PMID:9291580[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0031012

extracellular matrix

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001818
InterPro:IPR021190
InterPro:IPR021158

C

From MGI

GO:0031915

positive regulation of synaptic plasticity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

P

From MGI

GO:0032403

protein complex binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

F

From MGI

GO:0042493

response to drug

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

P

From MGI

GO:0043065

positive regulation of apoptotic process

MGI:MGI:3589495
PMID:15800063[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1932294

P

From MGI

GO:0043234

protein complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

C

From MGI

GO:0045766

positive regulation of angiogenesis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0048771

tissue remodeling

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

P

From MGI

GO:0051549

positive regulation of keratinocyte migration

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14780

P

From MGI

GO:0071460

cellular response to cell-matrix adhesion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50282

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Ortega N et al. (2005) Galectin-3 is a downstream regulator of matrix metalloproteinase-9 function during endochondral bone formation. Mol Biol Cell 16: 3028-39 PubMed GONUTS page
  2. 2.0 2.1 Leco KJ et al. (1997) Matrix metalloproteinase-9 maps to the distal end of chromosome 2 in the mouse. Dev Genet 21: 55-60 PubMed GONUTS page
  3. Webb DC et al. (2004) Polymorphisms in IL-4R alpha correlate with airways hyperreactivity, eosinophilia, and Ym protein expression in allergic IL-13-/- mice. J Immunol 172: 1092-8 PubMed GONUTS page
  4. Minamitani T et al. (2002) Adhesive defect in extracellular matrix tenascin-X-null fibroblasts: a possible mechanism of tumor invasion. Biol Pharm Bull 25: 1472-5 PubMed GONUTS page
  5. Hu SJ et al. (2008) MicroRNA expression and regulation in mouse uterus during embryo implantation. J Biol Chem 283: 23473-84 PubMed GONUTS page
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