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MGI:Mknk2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mknk2 ( synonyms: Mnk2 )
Protein Name(s) MAP kinase-interacting serine/threonine kinase 2,
External Links
MGI MGI:894279

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HBH9

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:87363
PMID:9155017[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:3688344
PMID:15102471[2]

IPI: Inferred from Physical Interaction

UniProtKB:P39429
UniProtKB:P63085

F

From MGI

GO:0005524

ATP binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HBH9

F

From MGI

GO:0005524

ATP binding

MGI:MGI:87363
PMID:9155017[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005622

intracellular

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HBH9

C

From MGI

GO:0005622

intracellular

MGI:MGI:87363
PMID:9155017[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0006417

regulation of translation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0810

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HBH9

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:87363
PMID:9155017[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:3793518
PMID:17903173[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007243

intracellular protein kinase cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HBH9

P

From MGI

GO:0007243

intracellular protein kinase cascade

MGI:MGI:87363
PMID:9155017[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0030097

hemopoiesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HBH9

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0071243

cellular response to arsenic-containing substance

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HBH9

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Waskiewicz AJ et al. (1997) Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2. EMBO J 16: 1909-20 PubMed GONUTS page
  2. Papin J & Subramaniam S (2004) Bioinformatics and cellular signaling. Curr Opin Biotechnol 15: 78-81 PubMed GONUTS page
  3. Chrestensen CA et al. (2007) Loss of MNK function sensitizes fibroblasts to serum-withdrawal induced apoptosis. Genes Cells 12: 1133-40 PubMed GONUTS page
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