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MGI:Mip
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Mip ( synonyms: Aqp0, aquaporin 0, lens opacity, Lop, MIP26, shrivelled, Svl ) | |
| Protein Name(s) | major intrinsic protein of eye lens fiber, | |
| External Links | ||
| MGI | MGI:96990 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002088 |
lens development in camera-type eye |
MGI:MGI:55175 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857105 |
P |
From MGI |
||
| GO:0005212 |
structural constituent of eye lens |
MGI:MGI:2670047 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005215 |
transporter activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3775669 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:3708206 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005792 |
microsome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:3760711 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:3775669 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005921 |
gap junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0303 |
C |
From MGI |
||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006810 |
transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006833 |
water transport |
MGI:MGI:2670047 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1861978 |
P |
From MGI |
||
| GO:0006833 |
water transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007154 |
cell communication |
MGI:MGI:3687441 |
NAS: Non-traceable Author Statement |
P |
From MGI |
|||
| GO:0007601 |
visual perception |
MGI:MGI:2670047 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1861978 |
P |
From MGI |
||
| GO:0015250 |
water channel activity |
MGI:MGI:2670047 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1861978 |
F |
From MGI |
||
| GO:0015250 |
water channel activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0015267 |
channel activity |
MGI:MGI:3687441 |
NAS: Non-traceable Author Statement |
F |
From MGI |
|||
| GO:0015722 |
canalicular bile acid transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:3687441 |
NAS: Non-traceable Author Statement |
C |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0046691 |
intracellular canaliculus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0050896 |
response to stimulus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0716 |
P |
From MGI |
||
| GO:0055085 |
transmembrane transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lyon MF et al. (1981) Lens opacity: a new gene for congenital cataract on chromosome 10 of the mouse. Genet Res 38: 337-41 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Shiels A et al. (2001) Optical dysfunction of the crystalline lens in aquaporin-0-deficient mice. Physiol Genomics 7: 179-86 PubMed GONUTS page
- ↑ 3.0 3.1 Xi JH et al. (2008) Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death. J Biol Chem 283: 5801-14 PubMed GONUTS page
- ↑ Varadaraj K et al. (2007) Functional expression of aquaporins in embryonic, postnatal, and adult mouse lenses. Dev Dyn 236: 1319-28 PubMed GONUTS page
- ↑ DePianto DJ et al. (2003) Analysis of non-crystallin lens fiber cell gene expression in c-Maf -/- mice. Mol Vis 9: 288-94 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Pisano MM & Chepelinsky AB (1991) Genomic cloning, complete nucleotide sequence, and structure of the human gene encoding the major intrinsic protein (MIP) of the lens. Genomics 11: 981-90 PubMed GONUTS page
