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MGI:Mink1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mink1 ( synonyms: Map4k6, MINK, Misshapen/NIKs-related kinase, Ysk2 )
Protein Name(s) misshapen-like kinase 1 (zebrafish),
External Links
MGI MGI:1355329

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0001952

regulation of cell-matrix adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N4C8

P

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:1354211
PMID:10708748[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N4C8

F

From MGI

GO:0005083

small GTPase regulator activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001180

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354211
PMID:10708748[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005622

intracellular

MGI:MGI:1354211
PMID:10708748[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N4C8

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N4C8

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:1354211
PMID:10708748[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006950

response to stress

MGI:MGI:1354211
PMID:10708748[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007243

intracellular protein kinase cascade

MGI:MGI:1354211
PMID:10708748[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007268

synaptic transmission

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001079459

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0022407

regulation of cell-cell adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N4C8

P

From MGI

GO:0030054

cell junction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0965

C

From MGI

GO:0030334

regulation of cell migration

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N4C8

P

From MGI

GO:0031532

actin cytoskeleton reorganization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N4C8

P

From MGI

GO:0042995

cell projection

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0966

C

From MGI

GO:0045060

negative thymic T cell selection

MGI:MGI:3521627
PMID:15608642[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0045202

synapse

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0770

C

From MGI

GO:0045211

postsynaptic membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0628

C

From MGI

GO:0046330

positive regulation of JNK cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N4C8

P

From MGI

GO:0046777

protein autophosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N4C8

P

From MGI

GO:0048813

dendrite morphogenesis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001079459

P

From MGI

GO:0050790

regulation of catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001180

P

From MGI

GO:2000311

regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001079459

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Dan I et al. (2000) Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development. FEBS Lett 469: 19-23 PubMed GONUTS page
  2. McCarty N et al. (2005) Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes. Nat Immunol 6: 65-72 PubMed GONUTS page
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