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MGI:Mfge8

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mfge8 ( synonyms: EGF/factor VIII, lactadherin, MFG-E8, Mfgm, SED1 )
Protein Name(s) milk fat globule-EGF factor 8 protein,
External Links
MGI MGI:102768

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001525

angiogenesis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0037

P

From MGI

GO:0001786

phosphatidylserine binding

MGI:MGI:2681272
PMID:12000961[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005178

integrin binding

MGI:MGI:2681272
PMID:12000961[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005178

integrin binding

MGI:MGI:5285150
PMID:20826760[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005615

extracellular space

MGI:MGI:2681272
PMID:12000961[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006910

phagocytosis, recognition

MGI:MGI:2681272
PMID:12000961[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006911

phagocytosis, engulfment

MGI:MGI:2681272
PMID:12000961[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007155

cell adhesion

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0130

P

From MGI

GO:0007155

cell adhesion

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000421

P

From MGI

GO:0007338

single fertilization

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0278

P

From MGI

GO:0008429

phosphatidylethanolamine binding

MGI:MGI:2681272
PMID:12000961[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:2681272
PMID:12000961[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0019897

extrinsic to plasma membrane

MGI:MGI:2681272
PMID:12000961[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0050766

positive regulation of phagocytosis

MGI:MGI:2681272
PMID:12000961[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:2000427

positive regulation of apoptotic cell clearance

MGI:MGI:5285150
PMID:20826760[2]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Hanayama R et al. (2002) Identification of a factor that links apoptotic cells to phagocytes. Nature 417: 182-7 PubMed GONUTS page
  2. 2.0 2.1 Friggeri A et al. (2010) HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin. Am J Physiol Cell Physiol 299: C1267-76 PubMed GONUTS page
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