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MGI:Mesdc2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mesdc2 ( synonyms: Mesd, msd )
Protein Name(s) mesoderm development candidate 2,
External Links
MGI MGI:1891421

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005783

endoplasmic reticulum

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0256

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:3610715
PMID:16263759[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006457

protein folding

MGI:MGI:3610715
PMID:16263759[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006457

protein folding

MGI:MGI:5285813
PMID:21397183[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007498

mesoderm development

MGI:MGI:1932260
PMID:11247670[3]

NAS: Non-traceable Author Statement

P

From MGI

GO:0016055

Wnt receptor signaling pathway

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0879

P

From MGI

GO:0034394

protein localization at cell surface

MGI:MGI:4365357
PMID:18505367[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050750

low-density lipoprotein particle receptor binding

MGI:MGI:3610715
PMID:16263759[1]

IPI: Inferred from Physical Interaction

UniProtKB:O75581

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Li Y et al. (2005) Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding. J Cell Sci 118: 5305-14 PubMed GONUTS page
  2. Chen J et al. (2011) Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6. Structure 19: 313-23 PubMed GONUTS page
  3. Wines ME et al. (2001) Identification of mesoderm development (mesd) candidate genes by comparative mapping and genome sequence analysis. Genomics 72: 88-98 PubMed GONUTS page
  4. Kubota T et al. (2008) Lrp6 hypomorphic mutation affects bone mass through bone resorption in mice and impairs interaction with Mesd. J Bone Miner Res 23: 1661-71 PubMed GONUTS page
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