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MGI:Mecp2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Mecp2 ( synonyms: Mbd5, WBP10 ) | |
| Protein Name(s) | methyl CpG binding protein 2, | |
| External Links | ||
| MGI | MGI:99918 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0000400 |
four-way junction DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0000790 |
nuclear chromatin |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0000792 |
heterochromatin |
MGI:MGI:2682084 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000792 |
heterochromatin |
MGI:MGI:3760176 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000792 |
heterochromatin |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0001662 |
behavioral fear response |
MGI:MGI:3663583 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158353 |
P |
From MGI |
||
| GO:0001662 |
behavioral fear response |
MGI:MGI:3800599 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3800596 |
P |
From MGI |
||
| GO:0001666 |
response to hypoxia |
MGI:MGI:3772310 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0001964 |
startle response |
MGI:MGI:3794508 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137555 |
P |
From MGI |
||
| GO:0001976 |
neurological system process involved in regulation of systemic arterial blood pressure |
MGI:MGI:3770320 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0002087 |
regulation of respiratory gaseous exchange by neurological system process |
MGI:MGI:3611090 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0002087 |
regulation of respiratory gaseous exchange by neurological system process |
MGI:MGI:3794508 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137555 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:3530434 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:3640022 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:3796314 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003682 |
chromatin binding |
MGI:MGI:3805223 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003682 |
chromatin binding |
MGI:MGI:3805223 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:3530434 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
F |
From MGI |
||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:3640022 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:3695672 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183727 |
F |
From MGI |
||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:3796314 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003729 |
mRNA binding |
MGI:MGI:3522407 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3700432 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5294529 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005623 |
cell |
MGI:MGI:3686581 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:2158884 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2679393 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3040528 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3040528 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3612318 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3663583 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3770752 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3772310 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3796314 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3805223 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3805223 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3770752 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:3612318 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006020 |
inositol metabolic process |
MGI:MGI:3769075 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0006122 |
mitochondrial electron transport, ubiquinol to cytochrome c |
MGI:MGI:3640022 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0006342 |
chromatin silencing |
MGI:MGI:3530434 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0006349 |
regulation of gene expression by genetic imprinting |
MGI:MGI:3530434 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:3612295 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0006541 |
glutamine metabolic process |
MGI:MGI:3769075 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0006576 |
cellular biogenic amine metabolic process |
MGI:MGI:3607765 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0006950 |
response to stress |
MGI:MGI:3695672 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183727 |
P |
From MGI |
||
| GO:0007268 |
synaptic transmission |
MGI:MGI:3611151 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183727 |
P |
From MGI |
||
| GO:0007416 |
synapse assembly |
MGI:MGI:3794248 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183727 |
P |
From MGI |
||
| GO:0007420 |
brain development |
MGI:MGI:3807442 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
P |
From MGI |
||
| GO:0007585 |
respiratory gaseous exchange |
MGI:MGI:1931684 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0007612 |
learning |
MGI:MGI:3794508 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137555 |
P |
From MGI |
||
| GO:0007612 |
learning |
MGI:MGI:3800599 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3800596 |
P |
From MGI |
||
| GO:0007613 |
memory |
MGI:MGI:3611151 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183727 |
P |
From MGI |
||
| GO:0007616 |
long-term memory |
MGI:MGI:3611151 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183727 |
P |
From MGI |
||
| GO:0008104 |
protein localization |
MGI:MGI:3760176 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0008134 |
transcription factor binding |
MGI:MGI:2679393 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0008211 |
glucocorticoid metabolic process |
MGI:MGI:3695672 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183727 |
P |
From MGI |
||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:3612318 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0008327 |
methyl-CpG binding |
MGI:MGI:3522407 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0008327 |
methyl-CpG binding |
MGI:MGI:3695672 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0008327 |
methyl-CpG binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008344 |
adult locomotory behavior |
MGI:MGI:1931684 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0008344 |
adult locomotory behavior |
MGI:MGI:3800599 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3800596 |
P |
From MGI |
||
| GO:0008542 |
visual learning |
MGI:MGI:3611151 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183727 |
P |
From MGI |
||
| GO:0009405 |
pathogenesis |
MGI:MGI:3772310 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0009790 |
embryo development |
MGI:MGI:79059 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0009791 |
post-embryonic development |
MGI:MGI:3800599 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3800596 |
P |
From MGI |
||
| GO:0010385 |
double-stranded methylated DNA binding |
MGI:MGI:2679393 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0010385 |
double-stranded methylated DNA binding |
MGI:MGI:3576944 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0010385 |
double-stranded methylated DNA binding |
MGI:MGI:3760176 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From MGI |
|||
| GO:0010385 |
double-stranded methylated DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0010468 |
regulation of gene expression |
MGI:MGI:3778555 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016358 |
dendrite development |
MGI:MGI:3512652 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
P |
From MGI |
||
| GO:0016358 |
dendrite development |
MGI:MGI:3789859 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
P |
From MGI |
||
| GO:0016571 |
histone methylation |
MGI:MGI:3530434 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0016573 |
histone acetylation |
MGI:MGI:3530434 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0019230 |
proprioception |
MGI:MGI:3794508 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137555 |
P |
From MGI |
||
| GO:0019230 |
proprioception |
MGI:MGI:3800599 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3800596 |
P |
From MGI |
||
| GO:0019233 |
sensory perception of pain |
MGI:MGI:3794508 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137555 |
P |
From MGI |
||
| GO:0019899 |
enzyme binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0019904 |
protein domain specific binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0021549 |
cerebellum development |
MGI:MGI:3807442 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
P |
From MGI |
||
| GO:0021591 |
ventricular system development |
MGI:MGI:3807442 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
P |
From MGI |
||
| GO:0030182 |
neuron differentiation |
MGI:MGI:3629530 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
P |
From MGI |
||
| GO:0031061 |
negative regulation of histone methylation |
MGI:MGI:3576944 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0031175 |
neuron projection development |
MGI:MGI:3629530 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
P |
From MGI |
||
| GO:0031490 |
chromatin DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0032048 |
cardiolipin metabolic process |
MGI:MGI:3769075 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0035067 |
negative regulation of histone acetylation |
MGI:MGI:3576944 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0035176 |
social behavior |
MGI:MGI:3663583 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158353 |
P |
From MGI |
||
| GO:0035176 |
social behavior |
MGI:MGI:3794508 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137555 |
P |
From MGI |
||
| GO:0035197 |
siRNA binding |
MGI:MGI:3522407 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0040029 |
regulation of gene expression, epigenetic |
MGI:MGI:3576944 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0040029 |
regulation of gene expression, epigenetic |
MGI:MGI:3789859 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
P |
From MGI |
||
| GO:0042551 |
neuron maturation |
MGI:MGI:3512652 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
P |
From MGI |
||
| GO:0042551 |
neuron maturation |
MGI:MGI:3789859 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
P |
From MGI |
||
| GO:0042551 |
neuron maturation |
MGI:MGI:3794248 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183727 |
P |
From MGI |
||
| GO:0043234 |
protein complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043524 |
negative regulation of neuron apoptotic process |
MGI:MGI:3772310 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0045322 |
unmethylated CpG binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:2158884 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:2448855 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:3530434 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:3686581 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
P |
From MGI |
||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:3695672 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183727 |
P |
From MGI |
||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:3796314 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:3800599 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3800596 |
P |
From MGI |
||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:3640022 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:3796314 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0046470 |
phosphatidylcholine metabolic process |
MGI:MGI:3769075 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0047485 |
protein N-terminus binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0048167 |
regulation of synaptic plasticity |
MGI:MGI:3611151 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183727 |
P |
From MGI |
||
| GO:0050432 |
catecholamine secretion |
MGI:MGI:3686581 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158354 |
P |
From MGI |
||
| GO:0050884 |
neuromuscular process controlling posture |
MGI:MGI:1931684 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0050905 |
neuromuscular process |
MGI:MGI:3663583 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158353 |
P |
From MGI |
||
| GO:0050905 |
neuromuscular process |
MGI:MGI:3800599 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3800596 |
P |
From MGI |
||
| GO:0051965 |
positive regulation of synapse assembly |
MGI:MGI:3762433 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0060079 |
regulation of excitatory postsynaptic membrane potential |
MGI:MGI:3762433 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
| GO:0060291 |
long-term synaptic potentiation |
MGI:MGI:3612295 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2137311 |
P |
From MGI |
||
|
colocalizes_with |
GO:0000792 |
heterochromatin |
MGI:MGI:3805223 |
IDA: Inferred from Direct Assay |
C |
From MGI |
||
|
colocalizes_with |
GO:0000792 |
heterochromatin |
MGI:MGI:3805223 |
IDA: Inferred from Direct Assay |
C |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Craig JM et al. (2003) Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns. Hum Mol Genet 12: 3109-21 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Nan X et al. (2007) Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation. Proc Natl Acad Sci U S A 104: 2709-14 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Gemelli T et al. (2006) Postnatal loss of methyl-CpG binding protein 2 in the forebrain is sufficient to mediate behavioral aspects of Rett syndrome in mice. Biol Psychiatry 59: 468-76 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Pelka GJ et al. (2006) Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice. Brain 129: 887-98 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Russell JC et al. (2007) Enhanced cell death in MeCP2 null cerebellar granule neurons exposed to excitotoxicity and hypoxia. Neuroscience 150: 563-74 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 Samaco RC et al. (2008) A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome. Hum Mol Genet 17: 1718-27 PubMed GONUTS page
- ↑ Bissonnette JM et al. (2007) Autonomic cardiovascular control in methyl-CpG-binding protein 2 (Mecp2) deficient mice. Auton Neurosci 136: 82-9 PubMed GONUTS page
- ↑ Viemari JC et al. (2005) Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice. J Neurosci 25: 11521-30 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 9.4 9.5 9.6 Horike S et al. (2005) Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. Nat Genet 37: 31-40 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 10.3 Kriaucionis S et al. (2006) Gene expression analysis exposes mitochondrial abnormalities in a mouse model of Rett syndrome. Mol Cell Biol 26: 5033-42 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 11.3 11.4 Chahrour M et al. (2008) MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 320: 1224-9 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 12.3 12.4 12.5 Kumar A et al. (2008) Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo. J Cell Sci 121: 1128-37 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 13.3 13.4 McGill BE et al. (2006) Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome. Proc Natl Acad Sci U S A 103: 18267-72 PubMed GONUTS page
- ↑ 14.0 14.1 14.2 Jeffery L & Nakielny S (2004) Components of the DNA methylation system of chromatin control are RNA-binding proteins. J Biol Chem 279: 49479-87 PubMed GONUTS page
- ↑ Harikrishnan KN et al. (2005) Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing. Nat Genet 37: 254-64 PubMed GONUTS page
- ↑ Kojic S et al. (2010) A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein. Arch Biochem Biophys 502: 60-7 PubMed GONUTS page
- ↑ 17.0 17.1 17.2 Wang H et al. (2006) Dysregulation of brain-derived neurotrophic factor expression and neurosecretory function in Mecp2 null mice. J Neurosci 26: 10911-5 PubMed GONUTS page
- ↑ 18.0 18.1 Shahbazian MD et al. (2002) Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation. Hum Mol Genet 11: 115-24 PubMed GONUTS page
- ↑ 19.0 19.1 19.2 Martinowich K et al. (2003) DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 302: 890-3 PubMed GONUTS page
- ↑ 20.0 20.1 Kriaucionis S & Bird A (2004) The major form of MeCP2 has a novel N-terminus generated by alternative splicing. Nucleic Acids Res 32: 1818-23 PubMed GONUTS page
- ↑ 21.0 21.1 21.2 Nagai K et al. (2005) A transcriptional repressor MeCP2 causing Rett syndrome is expressed in embryonic non-neuronal cells and controls their growth. Brain Res Dev Brain Res 157: 103-6 PubMed GONUTS page
- ↑ 22.0 22.1 Ruddock-D'Cruz NT et al. (2008) Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development. Mol Reprod Dev 75: 48-59 PubMed GONUTS page
- ↑ 23.0 23.1 23.2 23.3 Viola A et al. (2007) Metabolic fingerprints of altered brain growth, osmoregulation and neurotransmission in a Rett syndrome model. PLoS One 2: e157 PubMed GONUTS page
- ↑ 24.0 24.1 Asaka Y et al. (2006) Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome. Neurobiol Dis 21: 217-27 PubMed GONUTS page
- ↑ Ide S et al. (2005) Defect in normal developmental increase of the brain biogenic amine concentrations in the mecp2-null mouse. Neurosci Lett 386: 14-7 PubMed GONUTS page
- ↑ 26.0 26.1 26.2 26.3 26.4 Moretti P et al. (2006) Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome. J Neurosci 26: 319-27 PubMed GONUTS page
- ↑ 27.0 27.1 Palmer A et al. (2008) MeCP2 mutation causes distinguishable phases of acute and chronic defects in synaptogenesis and maintenance, respectively. Mol Cell Neurosci 37: 794-807 PubMed GONUTS page
- ↑ 28.0 28.1 28.2 Ward BC et al. (2008) Longitudinal brain MRI study in a mouse model of Rett Syndrome and the effects of choline. Neurobiol Dis 31: 110-9 PubMed GONUTS page
- ↑ 29.0 29.1 29.2 Guy J et al. (2001) A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 27: 322-6 PubMed GONUTS page
- ↑ Tate P et al. (1996) The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse. Nat Genet 12: 205-8 PubMed GONUTS page
- ↑ 31.0 31.1 31.2 31.3 Makedonski K et al. (2005) MeCP2 deficiency in Rett syndrome causes epigenetic aberrations at the PWS/AS imprinting center that affects UBE3A expression. Hum Mol Genet 14: 1049-58 PubMed GONUTS page
- ↑ Nomura T et al. (2008) MeCP2-dependent repression of an imprinted miR-184 released by depolarization. Hum Mol Genet 17: 1192-9 PubMed GONUTS page
- ↑ 33.0 33.1 Kishi N & Macklis JD (2004) MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions. Mol Cell Neurosci 27: 306-21 PubMed GONUTS page
- ↑ 34.0 34.1 34.2 Smrt RD et al. (2007) Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons. Neurobiol Dis 27: 77-89 PubMed GONUTS page
- ↑ 35.0 35.1 Matarazzo V et al. (2004) The transcriptional repressor Mecp2 regulates terminal neuronal differentiation. Mol Cell Neurosci 27: 44-58 PubMed GONUTS page
- ↑ Rountree MR et al. (2000) DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat Genet 25: 269-77 PubMed GONUTS page
- ↑ 37.0 37.1 Chao HT et al. (2007) MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number. Neuron 56: 58-65 PubMed GONUTS page
