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MGI:Mdk
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Mdk ( synonyms: Mek, MK ) | |
| Protein Name(s) | midkine, | |
| External Links | ||
| MGI | MGI:96949 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001662 |
behavioral fear response |
MGI:MGI:2178952 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007614 |
short-term memory |
MGI:MGI:2178952 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0008083 |
growth factor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0339 |
F |
From MGI |
||
| GO:0008083 |
growth factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000762 |
F |
From MGI |
||
| GO:0008201 |
heparin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0009611 |
response to wounding |
MGI:MGI:1353777 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0009611 |
response to wounding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_110486 |
P |
From MGI |
||
| GO:0016477 |
cell migration |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_110486 |
P |
From MGI |
||
| GO:0021681 |
cerebellar granular layer development |
MGI:MGI:2178952 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0021766 |
hippocampus development |
MGI:MGI:2178952 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0030325 |
adrenal gland development |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_110486 |
P |
From MGI |
||
| GO:0030421 |
defecation |
MGI:MGI:2178952 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043526 |
neuroprotection |
MGI:MGI:4943836 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:2178952 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0050795 |
regulation of behavior |
MGI:MGI:2178952 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0051781 |
positive regulation of cell division |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0497 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Nakamura E et al. (1998) Disruption of the midkine gene (Mdk) resulted in altered expression of a calcium binding protein in the hippocampus of infant mice and their abnormal behaviour. Genes Cells 3: 811-22 PubMed GONUTS page
- ↑ Horiba M et al. (2000) Neointima formation in a restenosis model is suppressed in midkine-deficient mice. J Clin Invest 105: 489-95 PubMed GONUTS page
- ↑ Kim YB et al. (2010) Midkine, heparin-binding growth factor, blocks kainic acid-induced seizure and neuronal cell death in mouse hippocampus. BMC Neurosci 11: 42 PubMed GONUTS page