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MGI:Mdh2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mdh2 ( synonyms: Mdh-2, Mor-1, Mor1 )
Protein Name(s) malate dehydrogenase 2, NAD (mitochondrial),
External Links
MGI MGI:97050

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016040

F

From MGI

GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR015955

F

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:E9PDB2

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:2682130
PMID:14651853[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3587122
PMID:15809022[2]

ISA: Inferred from Sequence Alignment

UniProtKB:P04634

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3852644
PMID:18614015[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04636

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:E9PDB2

C

From MGI

GO:0005743

mitochondrial inner membrane

MGI:MGI:3590069
PMID:12865426[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005759

mitochondrial matrix

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04636

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:E9PDB2

C

From MGI

GO:0005975

carbohydrate metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR015955

P

From MGI

GO:0006099

tricarboxylic acid cycle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04636

P

From MGI

GO:0006107

oxaloacetate metabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04636

P

From MGI

GO:0006108

malate metabolic process

MGI:MGI:3587122
PMID:15809022[2]

ISA: Inferred from Sequence Alignment

UniProtKB:P04634

P

From MGI

GO:0006108

malate metabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04636

P

From MGI

GO:0006108

malate metabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P40926

P

From MGI

GO:0006475

internal protein amino acid acetylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P40926

P

From MGI

GO:0006734

NADH metabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04636

P

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

F

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001236

F

From MGI

GO:0016615

malate dehydrogenase activity

MGI:MGI:3587122
PMID:15809022[2]

ISA: Inferred from Sequence Alignment

UniProtKB:P04634

F

From MGI

GO:0016615

malate dehydrogenase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04636

F

From MGI

GO:0016616

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001557
InterPro:IPR022383
InterPro:IPR015955

F

From MGI

GO:0030060

L-malate dehydrogenase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04636

F

From MGI

GO:0030060

L-malate dehydrogenase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P40926

F

From MGI

GO:0030060

L-malate dehydrogenase activity

MGI:MGI:53665
PMID:5496232[5]

IDA: Inferred from Direct Assay

F

From MGI

GO:0043621

protein self-association

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04636

F

From MGI

GO:0044262

cellular carbohydrate metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001557

P

From MGI

GO:0046554

malate dehydrogenase (NADP+) activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04636

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
  2. 2.0 2.1 2.2 Chow KM et al. (2005) Nardilysin facilitates complex formation between mitochondrial malate dehydrogenase and citrate synthase. Biochim Biophys Acta 1723: 292-301 PubMed GONUTS page
  3. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
  4. Da Cruz S et al. (2003) Proteomic analysis of the mouse liver mitochondrial inner membrane. J Biol Chem 278: 41566-71 PubMed GONUTS page
  5. Shows TB et al. (1970) Mitochondrial malate dehydrogenase and malic enzyme: Mendelian inherited electrophoretic variants in the mouse. Biochem Genet 4: 707-18 PubMed GONUTS page
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