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MGI:Mdfi

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mdfi ( synonyms: I-mf, I-mfa )
Protein Name(s) MyoD family inhibitor,
External Links
MGI MGI:107687

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4441142
PMID:11238923[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0005515

protein binding

MGI:MGI:3056015
PMID:15465018[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q62520

F

From MGI

GO:0005515

protein binding

MGI:MGI:4441137
PMID:12192039[3]

IPI: Inferred from Physical Interaction

UniProtKB:O15169

F

From MGI

GO:0005634

nucleus

MGI:MGI:4441142
PMID:11238923[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0007257

activation of JUN kinase activity

MGI:MGI:4441137
PMID:12192039[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0008134

transcription factor binding

MGI:MGI:4441137
PMID:12192039[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q9UJU2

F

From MGI

GO:0008134

transcription factor binding

MGI:MGI:4441142
PMID:11238923[1]

IPI: Inferred from Physical Interaction

UniProtKB:P70062

F

From MGI

GO:0009950

dorsal/ventral axis specification

MGI:MGI:4441142
PMID:11238923[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030111

regulation of Wnt receptor signaling pathway

MGI:MGI:4441137
PMID:12192039[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0030178

negative regulation of Wnt receptor signaling pathway

MGI:MGI:4441142
PMID:11238923[1]

IGI: Inferred from Genetic Interaction

UniProtKB:P70062

P

From MGI

GO:0043392

negative regulation of DNA binding

MGI:MGI:4441142
PMID:11238923[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0048704

embryonic skeletal system morphogenesis

MGI:MGI:1312999
PMID:9799236[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2155446

P

From MGI

GO:0060707

trophoblast giant cell differentiation

MGI:MGI:1312999
PMID:9799236[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2155446

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Snider L et al. (2001) Inhibition of Tcf3 binding by I-mfa domain proteins. Mol Cell Biol 21: 1866-73 PubMed GONUTS page
  2. Ishiguro A et al. (2004) Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family. Biochem Biophys Res Commun 324: 302-7 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Kusano S & Raab-Traub N (2002) I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways. Mol Cell Biol 22: 6393-405 PubMed GONUTS page
  4. 4.0 4.1 Kraut N et al. (1998) Requirement of the mouse I-mfa gene for placental development and skeletal patterning. EMBO J 17: 6276-88 PubMed GONUTS page
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